Rabbit Polyclonal SNX33 antibody. Suitable for IP and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SNX33 aa 50-150.
pH: 6.8 - 7.4
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 0.1% BSA
IP | |
---|---|
Human | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info - | Notes 8 - 15 μl/mg lysate |
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Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes.
SH3PX3, SH3PXD3C, SNX30, SNX33, Sorting nexin-33, SH3 and PX domain-containing protein 3
Rabbit Polyclonal SNX33 antibody. Suitable for IP and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SNX33 aa 50-150.
pH: 6.8 - 7.4
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 0.1% BSA
ab241201 was affinity purified using an epitope specific to SNX33 immobilized on solid support.
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SNX33 was immunoprecipitated from MCF7 (human breast adenocarcinoma cell line) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab241201 at 8 μl/reaction. Western blot was performed from the immunoprecipitate using ab241201 at 1/400 dilution.
Lane 1: ab241201 IP in MCF7 whole cell lysate.
Lane 2: Control IgG IP in MCF7 whole cell lysate.
Detection: Chemiluminescence with exposure time of 30 seconds.
Lysates prepared in NETN buffer.
All lanes: Immunoprecipitation - Anti-SNX33 antibody (ab241201)
Predicted band size: 65 kDa
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