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AB39327

Anti-SOAT 1/ACAT1 antibody

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(16 Publications)

Rabbit Polyclonal SOAT 1/ACAT1 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 16 publications.

View Alternative Names

ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT, SOAT1, Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, Cholesterol acyltransferase 1, ACAT-1

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOAT 1/ACAT1 antibody (AB39327)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOAT 1/ACAT1 antibody (AB39327)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human adreanal tissue using ab39327 at 1/200 after heat induced antigen reteval in pH 6.0 citrate buffer. DAB staining.

Western blot - Anti-SOAT 1/ACAT1 antibody (AB39327)
  • WB

Unknown

Western blot - Anti-SOAT 1/ACAT1 antibody (AB39327)

The 65 kDa band detected is the native form of ACAT1.

All lanes:

Western blot - Anti-SOAT 1/ACAT1 antibody (ab39327)

Lane 1:

Rat Liver (30µg)

Lane 2:

HepG2 cell lysate (30µg)

Predicted band size: 65 kDa

Observed band size: 50 kDa,65 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

IHC-P, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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AB65359

Cholesterol/ Cholesteryl Ester Assay Kit - Quantitation

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2 Reviews

View product

We recommend this product because it’s often used in the same experiment or related research.

We advise that you always check the datasheet to ensure it fits your experiments, or contact ourtechnical teamfor help.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed : 16154994, PubMed : 16647063, PubMed : 32433613, PubMed : 32433614, PubMed : 32944968, PubMed : 9020103). Plays a role in lipoprotein assembly and dietary cholesterol absorption (PubMed : 16154994, PubMed : 9020103). Preferentially utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) as a substrate : shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions (PubMed : 11294643, PubMed : 32433614).
See full target information SOAT1
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Publications (16)

Recent publications for all applications. Explore the full list and refine your search

Oncology letters 25:231 PubMed37153054

2023

Evaluation of sterol‑o‑acyl transferase 1 and cholesterol ester levels in plasma, peritoneal fluid and tumor tissue of patients with endometrial cancer: A pilot study.

Applications

Unspecified application

Species

Unspecified reactive species

Vijayalakshmi N Ayyagari,Miao Li,Paula Diaz-Sylvester,Kathleen Groesch,Teresa Wilson,Zvi Pasman,Ejaz M Shah,Andrea Braundmeier-Fleming,Laurent Brard

BMC cancer 22:387 PubMed35399074

2022

Assessment of the diagnostic and prognostic relevance of ACAT1 and CE levels in plasma, peritoneal fluid and tumor tissue of epithelial ovarian cancer patients - a pilot study.

Applications

Unspecified application

Species

Unspecified reactive species

Vijayalakshmi Ayyagari,Maio Li,Zvi Pasman,Xinjia Wang,Somaja Louis,Paula Diaz-Sylvester,Kathleen Groesch,Teresa Wilson,Laurent Brard

Aging 14:2678-2694 PubMed35354120

2022

piRNA-6426 increases DNMT3B-mediated SOAT1 methylation and improves heart failure.

Applications

Unspecified application

Species

Unspecified reactive species

Nier Zhong,Xiting Nong,Jiayu Diao,Guang Yang

International journal of molecular sciences 23: PubMed35409086

2022

SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?

Applications

Unspecified application

Species

Unspecified reactive species

Mario Löhr,Wolfgang Härtig,Almut Schulze,Matthias Kroiß,Silviu Sbiera,Constantin Lapa,Bianca Mages,Sabrina Strobel,Jennifer Elisabeth Hundt,Simone Bohnert,Stefan Kircher,Sudha Janaki-Raman,Camelia-Maria Monoranu

Frontiers in pharmacology 12:769647 PubMed34790132

2021

SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.

Applications

Unspecified application

Species

Unspecified reactive species

Tingting Zhu,Zhangding Wang,Tianhui Zou,Lei Xu,Shu Zhang,Yali Chen,Chen Chen,Weijie Zhang,Shouyu Wang,Qingqing Ding,Guifang Xu

Prostate cancer and prostatic diseases 25:484-490 PubMed34326474

2021

High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Carolin Eckhardt,Iuliu Sbiera,Markus Krebs,Silviu Sbiera,Martin Spahn,Burkhard Kneitz,Steven Joniau,Martin Fassnacht,Hubert Kübler,Isabel Weigand,Matthias Kroiss

iScience 24:102722 PubMed34258555

2021

Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangyu Li,Woonghee Kim,Kajetan Juszczak,Muhammad Arif,Yusuke Sato,Haruki Kume,Seishi Ogawa,Hasan Turkez,Jan Boren,Jens Nielsen,Mathias Uhlen,Cheng Zhang,Adil Mardinoglu

The Journal of clinical endocrinology and metabolism 105: PubMed32449514

2020

Expression of SOAT1 in Adrenocortical Carcinoma and Response to Mitotane Monotherapy: An ENSAT Multicenter Study.

Applications

Unspecified application

Species

Unspecified reactive species

Isabel Weigand,Barbara Altieri,Amanda M F Lacombe,Vittoria Basile,Stefan Kircher,Laura-Sophie Landwehr,Jochen Schreiner,Maria C N Zerbini,Cristina L Ronchi,Felix Megerle,Alfredo Berruti,Letizia Canu,Marco Volante,Isabel Paiva,Silvia Della Casa,Silviu Sbiera,Martin Fassnacht,Maria Candida B V Fragoso,Massimo Terzolo,Matthias Kroiss

Cancers 12: PubMed31963898

2020

Sterol O-Acyl Transferase 1 as a Prognostic Marker of Adrenocortical Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Amanda Meneses Ferreira Lacombe,Iberê Cauduro Soares,Beatriz Marinho de Paula Mariani,Mirian Yumie Nishi,João Evangelista Bezerra-Neto,Helaine da Silva Charchar,Vania Balderrama Brondani,Fabio Tanno,Victor Srougi,José Luiz Chambo,Ricardo Miguel Costa de Freitas,Berenice Bilharinho Mendonca,Ana O Hoff,Madson Q Almeida,Isabel Weigand,Matthias Kroiss,Maria Claudia Nogueira Zerbini,Maria Candida Barisson Villares Fragoso

The Journal of clinical endocrinology and metabolism 105: PubMed31586196

2019

The Efficacy of Mitotane in Human Primary Adrenocortical Carcinoma Cultures.

Applications

Unspecified application

Species

Unspecified reactive species

Peter M van Koetsveld,Sara G Creemers,Fadime Dogan,Gaston J H Franssen,Wouter W de Herder,Richard A Feelders,Leo J Hofland
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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