Anti-Somatostatin Receptor 3/SSTR3 antibody
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(4 Publications)
Rabbit Polyclonal Somatostatin Receptor 3/SSTR3 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human SSTR3 aa 350-400.
View Alternative Names
Somatostatin receptor type 3, SS-3-R, SS3-R, SS3R, SST3, SSR-28, SSTR3
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Somatostatin Receptor 3/SSTR3 antibody (AB28680)
ab28680, at a dilution of 1/2500, staining Human pancreatic islands by Immunohistochemistry.
Reactivity data
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Biological function summary
SSTR3 plays an important role in inhibiting the release of several other hormones and neurotransmitters like growth hormone and glucagon which helps regulate endocrine and nervous system activities. It functions as part of a complex system that includes other somatostatin receptors. By interacting with these systems SSTR3 influences processes such as cell proliferation neurotransmission and the modulation of cyclic AMP levels. Due to its inhibitory function the receptor helps maintain balance in hormone secretion and neural activity.
Pathways
SSTR3 receptor signaling integrates into the somatostatin signaling pathway an important process in hormone secretion regulation. It works closely with other receptors like SSTR2 together mediating somatostatin effects throughout the body. The receptor is also involved in the MAPK signaling pathway which has roles in cellular responses to various stimuli. These pathways contribute to its ability to modulate growth apoptosis and neuronal signaling.
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Publications (4)
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Journal of neuroendocrinology 34:e13109 PubMed35304807
2022
Applications
Unspecified application
Species
Unspecified reactive species
EJNMMI research 5:25 PubMed25977882
2015
Applications
IHC
Species
Unspecified reactive species
Annals of oncology : official journal of the Europ 21:548-555 PubMed19759190
2009
Applications
IHC
Species
Human
Modern pathology : an official journal of the Unit 20:1172-82 PubMed17873898
2007
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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