Rabbit Polyclonal SOX1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 25 publications.
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Publications
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- Nature communications 14:76742023A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSebastian Schmidt,Constantin Stautner,Duc Tung Vu,Alexander Heinz,Martin Regensburger,Ozge Karayel,Dietrich Trümbach,Anna Artati,Sabine Kaltenhäuser,Mohamed Zakaria Nassef,Sina Hembach,Letyfee Steinert,Beate Winner,Winkler Jürgen,Martin Jastroch,Malte D Luecken,Fabian J Theis,Gil Gregor Westmeyer,Jerzy Adamski,Matthias Mann,Karsten Hiller,Florian Giesert,Daniela M Vogt Weisenhorn,Wolfgang WurstPubMed 37996418
- International journal of molecular sciences 23:2022PLEKHM2 Loss of Function Impairs the Activity of iPSC-Derived Neurons via Regulation of Autophagic Flux.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHadas Ben-Zvi,Tatiana Rabinski,Rivka Ofir,Smadar Cohen,Gad D VatinePubMed 36555735
- The Journal of biological chemistry 298:1021062022Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMin Zhang,Yang Liu,Lihua Shi,Lei Fang,Liyang Xu,Ying CaoPubMed 35671824
- Science advances 7:2021Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCharles-Francois V Latchoumane,Martha I Betancur,Gregory A Simchick,Min Kyoung Sun,Rameen Forghani,Christopher E Lenear,Aws Ahmed,Ramya Mohankumar,Nivedha Balaji,Hannah D Mason,Stephanie A Archer-Hartmann,Parastoo Azadi,Philip V Holmes,Qun Zhao,Ravi V Bellamkonda,Lohitash KarumbaiahPubMed 33674306
- Molecular therapy oncolytics 20:147-1652021Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of and genes in glioma SCs .Applications:Unspecified applicationReactive species:Unspecified reactive speciesNazneen Aslam,Elham Abusharieh,Duaa Abuarqoub,Dema Ali,Dana Al-Hattab,Suha Wehaibi,Ban Al-Kurdi,Fatima Jamali,Walhan Alshaer,Hanan Jafar,Abdalla S AwidiPubMed 33575478
- Neural regeneration research 16:653-6582020Neurons derived from human-induced pluripotent stem cells express mu and kappa opioid receptors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZhi-Hai Ju,Xuan Liang,Yao-Yao Ren,Luo-Wa Shu,Yan-Hong Yan,Xu CuiPubMed 33063716
- Journal of cellular and molecular medicine 24:5146-51512020Odontogenesis and neuronal differentiation characteristics of periodontal ligament stem cells from beagle dog.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaojie Li et. al.PubMed 32202359
- Wellcome open research 5:162020human stem cell derived cultures to monitor calcium signaling in neuronal development and function.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYojet Sharma et. al.PubMed 32195361
- FASEB journal : official publication of the Federa 33:11973-119922019Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMeghan T Logun et. al.PubMed 31398290
- Frontiers in genetics 10:4222019EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Consider this alternative
Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Predicted | Expected | Expected |
| Mouse | Tested | Expected | Expected |
| Rat | Predicted | Expected | Expected |
| Chimpanzee | Predicted | Predicted | Predicted |
| Dog | Predicted | Predicted | Predicted |
| Orangutan | Predicted | Predicted | Predicted |
| Rabbit | Predicted | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat, Rabbit, Dog, Human, Chimpanzee, Orangutan | Dilution info - | Notes - |
IHC-P
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Human | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rabbit, Dog, Chimpanzee, Orangutan | Dilution info - | Notes - |
ICC/IF
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Human | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rabbit, Dog, Chimpanzee, Orangutan | Dilution info - | Notes - |
Associated Products
Select an associated product type
4 products for Alternative Product
Target data
Function
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Alternative names
Transcription factor SOX-1, SOX1
Recommended products
Rabbit Polyclonal SOX1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 25 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
Western blot - Anti-SOX1 antibody (ab87775)
This blot was produced using a 4-12% Bis-tris gel under the MOPS buffer system. The gel was run at 200V for 50 minutes before being transferred onto a Nitrocellulose membrane at 30V for 70 minutes. The membrane was then blocked for an hour using 2% BSA before being incubated with ab87775 overnight at 4°C. Antibody binding was detected using an anti-rabbit HRP secondary antibody (Goat Anti-Rabbit IgG H&L (HRP) ab6721), and visualised using ECL development solution ECL Substrate Kit (High Sensitivity) ab133406.
All lanes: Western blot - Anti-SOX1 antibody (ab87775) at 1 µg/mL
Lane 1: E14Tg2a (Mouse embryonic stem cell line) Whole Cell Lysate at 10 µg
Lane 2: 46C (Mouse embryonic stem cell line) Whole Cell Lysate at 10 µg
SecondaryAll lanes: Goat Anti-Rabbit IgG H&L (HRP) at 1/50000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 39 kDa
Observed band size: 40 kDa, 45 kDa
Exposure time: 8min
This image is courtesy of a customer review by Patrick Ovando RocheWestern blot - Anti-SOX1 antibody (ab87775)
All lanes: Western blot - Anti-SOX1 antibody (ab87775) at 1/1000 dilution
Lane 1: H1 Human embryonic stem cells at 20 µg
Lane 2: H1 Human embryonic stem cell derived neural progenitor stem cells at 20 µg
SecondaryAll lanes: Mouse anti-rabbit HRP conjugated at 1/20000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 39 kDa
Observed band size: 50 kDa
Exposure time: 30s
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