AB180228

Anti-SOX10 antibody

Name: Anti-SOX10 antibody (ab180228) | Abcam
Brand: Abcam Limited
SKU: AB180228
Rating: 1 (1 reviews)

(1 Review)

(1 Publication)

Goat Polyclonal SOX10 antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human SOX10 aa 350-400.

View Alternative Names

Transcription factor SOX-10, SOX10

2 Images

Supplier Data

Western blot - Anti-SOX10 antibody (AB180228)

Primary incubation was 1 hour.

All lanes:

Western blot - Anti-SOX10 antibody (ab180228) at 0.1 µg/mL

All lanes:

Human brain cerebellum lysate (in RIPA buffer) at 35 µg

Predicted band size: 49 kDa

Observed band size: 48 kDa

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Supplier Data

Western blot - Anti-SOX10 antibody (AB180228)

Primary incubation 1 hour at room temperature.

All lanes:

Western blot - Anti-SOX10 antibody (ab180228) at 0.1 µg/mL

All lanes:

Mouse brain lysate in RIPA buffer at 35 µg

Predicted band size: 49 kDa

Observed band size: 52 kDa

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Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

applications

Immunogen

Synthetic Peptide within Human SOX10 aa 350-400. The exact immunogen used to generate this antibody is proprietary information.

P56693

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.03-0.1 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.03-0.1 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

ab180228 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed : 21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).

See full target information SOX10

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 13:887822 PubMed35586041

2022

LINC00586 Represses ASXL1 Expression Thus Inducing Epithelial-To-Mesenchymal Transition of Colorectal Cancer Cells Through LSD1-Mediated H3K4me2 Demethylation.

Applications

Unspecified application

Species

Unspecified reactive species

Fengting Liu,Xiaofang Ma,Xiyun Bian,Chunyan Zhang,Xiaozhi Liu,Qiang Liu

View all publications

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Product promise

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