Anti-SOX10 antibody [BC34] is a mouse monoclonal antibody used to detect SOX10 in immunohistochemistry on paraffin-embedded sections (IHC-P). Reacts with human samples.
Images
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (AB195364), expandable thumbnail](https://content.abcam.com/products/images/sox10-antibody-bc34-ab195364--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img111840.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (AB195364)")
Key facts
- Isotype
IgG1
- Host species
Mouse
- Storage buffer
Preservative: 0.099% Sodium azide
Constituents: 99% Water- Form
Liquid
- Clonality
Monoclonal
Immunogen
- Recombinant Fragment Protein within Human SOX10. The exact immunogen used to generate this antibody is proprietary information. Database link P56693
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100.00000 - 1/200.00000 | Notes Perform heat-mediated antigen retrieval before commencing with IHC staining protocol. |
Associated Products
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Target data
Function
Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
Alternative names
Transcription factor SOX-10, SOX10
Recommended products
Anti-SOX10 antibody [BC34] is a mouse monoclonal antibody used to detect SOX10 in immunohistochemistry on paraffin-embedded sections (IHC-P). Reacts with human samples.
Key facts
- Isotype
IgG1
- Host species
Mouse
- Storage buffer
Preservative: 0.099% Sodium azide
Constituents: 99% Water- Form
Liquid
- Clonality
Monoclonal
- Immunogen
- Recombinant Fragment Protein within Human SOX10. The exact immunogen used to generate this antibody is proprietary information. Database link P56693
- Clone number
BC34
- Purification technique
Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
This product was changed from ascites to tissue culture supernatant on 14/07/17. The following lots are from ascites and are still in stock as of 14/07/17 – GR300901. Lot numbers higher than GR300901 will be from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly.
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Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (ab195364), expandable thumbnail](https://content.abcam.com/products/images/sox10-antibody-bc34-ab195364--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img111840.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (ab195364)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (ab195364)
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded spindle cell melanoma (DAB, left image) and pigmented melanoma (fast red, right image) labeling SOX10 with ab195364 at a 1/100 dilution.
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