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AB195364

Anti-SOX10 antibody [BC34]

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(1 Publication)

Anti-SOX10 antibody [BC34] (ab195364) is a mouse monoclonal antibody detecting SOX10 in IHC-P. Suitable for Human.

View Alternative Names

Transcription factor SOX-10, SOX10

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (AB195364)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [BC34] (AB195364)

Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded spindle cell melanoma (DAB, left image) and pigmented melanoma (fast red, right image) labeling SOX10 with ab195364 at a 1/100 dilution.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

BC34

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human SOX10. The exact immunogen used to generate this antibody is proprietary information.

P56693

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }
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Product details

Product Specifications
Anti-SOX10 antibody [BC34] (ab195364) is a mouse monoclonal antibody and is validated for use in IHC-P in human samples.
Anti-SOX10 antibody [BC34] (ab195364) specifically detects SOX10 (UniProt ID: P56693; Molecular weight: 50kDa) and is sold in 100µL selling sizes.

Quality and Validation
Abcam's high quality validation processes ensure Anti-SOX10 antibody [BC34] (ab195364) has high sensitivity and specificity.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
Preservative: 0.099% Sodium azide Constituents: 99% Water
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed : 21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
See full target information SOX10
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

iScience 28:111994 PubMed40071147

2025

IQGAP2 regulates blood-brain barrier immune dynamics.

Applications

Unspecified application

Species

Unspecified reactive species

Ketaki A Katdare,Andrew Kjar,Natasha M O'Brown,Emma H Neal,Alexander G Sorets,Alena Shostak,Wilber Romero-Fernandez,Alexander J Kwiatkowski,Kate Mlouk,Hyosung Kim,Rebecca P Cowell,Katrina R Schwensen,Cristian O Carvajal Tapia,Guste Venslovaite,Kensley B Horner,John T Wilson,Matthew S Schrag,Sean G Megason,Ethan S Lippmann
View all publications
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Product promise

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