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AB229185

Anti-SOX11 antibody [EPR20457]

3

(2 Reviews)

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(6 Publications)

Rabbit Recombinant Monoclonal SOX11 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 6 publications.

View Alternative Names

Transcription factor SOX-11, SOX11

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [EPR20457] (AB229185)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [EPR20457] (AB229185)

Immunohistochemical analysis of paraffin-embedded human mantle cell lymphoma tissue labeling SOX11 with ab229185 at 1/250 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Nucleus staining in human mantle cell lymphoma (PMID : 19880788. PMID : 17934069) is observed. Counterstained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [EPR20457] (AB229185)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [EPR20457] (AB229185)

Immunohistochemical analysis of paraffin-embedded human glioma tissue labeling SOX11 with ab229185 at 1/250 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Nucleus staining on human glioma (PMID : 15583815.) is observed. Counterstained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

Western blot - Anti-SOX11 antibody [EPR20457] (AB229185)
  • WB

Supplier Data

Western blot - Anti-SOX11 antibody [EPR20457] (AB229185)

Exposure time : Lane 1 : 1 minute, Lane 2 : 3 minutes.

Blocking/Dilution buffer : 5% NFDM/TBST.

The molecular weight observed is phosphorylated form, consistent with what has been described in the literature. (PMID : 19880779, PMID : 29973868).

All lanes:

Western blot - Anti-SOX11 antibody [EPR20457] (ab229185) at 1/1000 dilution

Lane 1:

SH-SY5Y (human neuroblastoma cell line from bone marrow) whole cell lysate at 20 µg

Lane 2:

Human fetal brain lysate at 10 µg

Secondary

All lanes:

Western blot - VeriBlot for IP Detection Reagent (HRP) (<a href='/en-us/products/reagents/veriblot-for-ip-detection-reagent-hrp-ab131366'>ab131366</a>) at 1/1000 dilution

Predicted band size: 47 kDa

false

  • Carrier free

    Anti-SOX11 antibody [EPR20457] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR20457

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/250", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcription factor that acts as a transcriptional activator (PubMed : 24886874, PubMed : 26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).
See full target information SOX11
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

International dental journal 75:100872 PubMed40543136

2025

SOX11 and GLIS2: Novel Biomarkers for Understanding the Progression of Oral Leukoplakia.

Applications

Unspecified application

Species

Unspecified reactive species

Yi Li,Zhencun Tang,Chenliang Xiao,Jun Su,Lijia He,Wenyun Zhang

Nature 638:469-478 PubMed39814878

2025

Specification of claustro-amygdalar and palaeocortical neurons and circuits.

Applications

Unspecified application

Species

Unspecified reactive species

Navjot Kaur,Rothem Kovner,Forrest O Gulden,Mihovil Pletikos,David Andrijevic,Tianjia Zhu,John Silbereis,Mikihito Shibata,Akemi Shibata,Yuting Liu,Shaojie Ma,Nikkita Salla,Xabier de Martin,Thomas S Klarić,Megan Burke,Daniel Franjic,Hyesun Cho,Matthew Yuen,Ipsita Chatterjee,Paula Soric,Devippriya Esakkimuthu,Markus Moser,Gabriel Santpere,Yann S Mineur,Kartik Pattabiraman,Marina R Picciotto,Hao Huang,Nenad Sestan

Aging 16:3896-3914 PubMed38407972

2024

GAS5, a long noncoding RNA, contributes to annulus fibroblast osteogenic differentiation and apoptosis in intervertebral disk degeneration via the miR-221-3p/SOX11 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Qi Liu,Jiaying Luo,Huan Wang,Lei Zhang,Jingwen Guo,Guoxin Jin

Cancers 14: PubMed36551589

2022

Systematic Investigation of the Multifaceted Role of in Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Qingqing Sun,Jun Du,Jie Dong,Shuaikang Pan,Hongwei Jin,Xinghua Han,Jinguo Zhang

Cancer cell international 22:31 PubMed35033084

2022

MiR-937-3p promotes metastasis and angiogenesis and is activated by MYC in lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zijian Ma,Ganyi Chen,Yiqian Chen,Zizhang Guo,Hao Chai,Yu Tang,Lin Zheng,Ke Wei,Chunfeng Pan,Zhifei Ma,Yang Xia,Aiping Zhang

Cell biochemistry and function 37:608-617 PubMed31502671

2019

Suppression of PRPF4 regulates pluripotency, proliferation, and differentiation in mouse embryonic stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Song Park,Se-Hyeon Han,Hyeon-Gyeom Kim,Jain Jeong,Minjee Choi,Hee-Yeon Kim,Min-Gi Kim,Jin-Kyu Park,Jee Eun Han,Gil-Jae Cho,Myoung Ok Kim,Zae Young Ryoo,Seong-Kyoon Choi
View all publications
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