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AB170916

Anti-SOX11 antibody [EPR8191(2)]

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(10 Publications)

Rabbit Recombinant Monoclonal SOX11 antibody. Suitable for IP, WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 10 publications.

View Alternative Names

Transcription factor SOX-11, SOX11

3 Images
Flow Cytometry (Intracellular) - Anti-SOX11 antibody [EPR8191(2)] (AB170916)
  • Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-SOX11 antibody [EPR8191(2)] (AB170916)

Intracellular Flow Cytometry analysis of SH-SY5Y (Human neuroblastoma epithelial cell) cells labeling SOX11 (red) with ab170916 at a 1/60 dilution. Cells were fixed with 4% paraformaldehyde and permeabilized with 90% methanol. A goat anti-rabbit IgG (Alexa Fluor® 488) (ab150077) was used as the secondary antibody at a 1/2000 dilution. Black - Rabbit monoclonal IgG (Black) (ab172730). Blue (unlabeled control) - Cell without incubation with primary antibody and secondary antibody (Blue).

Immunoprecipitation - Anti-SOX11 antibody [EPR8191(2)] (AB170916)
  • IP

Supplier Data

Immunoprecipitation - Anti-SOX11 antibody [EPR8191(2)] (AB170916)

Lane 1 Primary : ab170916, 1/1000 dilution
Sample : Immunoprecipitation pellet from Human fetal brain lysate using ab170916 at 1/10.
Secondary : HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.

Lane 2 Primary : ab170916, 1/1000 dilution
Sample : Immunoprecipitation pellet from PBS using ab170916 at 1/10 (negative control).
Secondary : HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit

All lanes:

Immunoprecipitation - Anti-SOX11 antibody [EPR8191(2)] (ab170916)

Predicted band size: 47 kDa

true

Western blot - Anti-SOX11 antibody [EPR8191(2)] (AB170916)
  • WB

Supplier Data

Western blot - Anti-SOX11 antibody [EPR8191(2)] (AB170916)

All lanes:

Western blot - Anti-SOX11 antibody [EPR8191(2)] (ab170916) at 1/1000 dilution

Lane 1:

Human fetal brain tissue lysate at 10 µg

Lane 2:

SH-SY5Y cell lysate at 10 µg

Lane 3:

Y79 cell lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Predicted band size: 47 kDa

true

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR8191(2)

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP, WB, Flow Cyt (Intra)

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "IHC" : {"fullname" : "Immunohistochemistry", "shortname":"IHC"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/10 - 1/100", "IP-species-notes": "<p></p>", "IHC-species-checked": "notRecommended", "IHC-species-dilution-info": "", "IHC-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/60", "FlowCytIntra-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "IHC-species-checked": "notRecommended", "IHC-species-dilution-info": "", "IHC-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "IHC-species-checked": "notRecommended", "IHC-species-dilution-info": "", "IHC-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcription factor that acts as a transcriptional activator (PubMed : 24886874, PubMed : 26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).
See full target information SOX11
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Publications (10)

Recent publications for all applications. Explore the full list and refine your search

Annals of surgical treatment and research 106:284-295 PubMed38725807

2024

Effects of transcription factor on the biological behavior of neuroblastoma cell and potential regulatory mechanism.

Applications

Unspecified application

Species

Unspecified reactive species

Jing-Ru Huang,Yong Li,Peng Chen,Ji-Xiu Wei,Xia Yang,Qiong-Qian Xu,Jia-Bo Chen

PeerJ 11:e16593 PubMed38084140

2023

Inhibition of hepatocellular carcinoma growth modulation of the miR-221/SOX11 axis by curcumin and berberine.

Applications

Unspecified application

Species

Unspecified reactive species

Sheng Li,Xiaoliang Cai,Liang Chen,Manbian Lin,Ziqi Zhu,Huihuang Xiao,Pingping Nie,Quanwen Chen,Xiaoyu Yang

NPJ Regenerative medicine 7:53 PubMed36114225

2022

Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment.

Applications

Unspecified application

Species

Unspecified reactive species

Ye Sun,Jie Zhao,Qiang Wu,Yuxin Zhang,Yongqing You,Wenbo Jiang,Kerong Dai

Molecular therapy oncolytics 24:834-848 PubMed35317520

2022

LINC01296 promotes neuroblastoma tumorigenesis via the NCL-SOX11 regulatory complex.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Wang,Zuopeng Wang,Weihong Lin,Qilei Han,Hanlei Yan,Wei Yao,Rui Dong,Deshui Jia,Kuiran Dong,Kai Li

Oncology letters 22:709 PubMed34457064

2021

Association between miR-212-3p and SOX11, and the effects of miR-212-3p on cell proliferation and migration in mantle cell lymphoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuyang Tian,Li Wang,Yanming Zhang,Lianqiao Li,Yingying Fei,Xingxia Zhang,Guoqiang Lin

International journal of molecular medicine 47:361-373 PubMed33236128

2020

SOX11 and FAK participate in the stretch‑induced mechanical injury to alveolar type 2 epithelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Mingxing Fang,Tieling Xu,Shujuan Fan,Na Liu,Luping Li,Junxia Gao,Wenbin Li

American journal of translational research 12:4354-4370 PubMed32913511

2020

Rho-kinase inhibition by Fasudil promotes tumor maturation and apoptosis in small-cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Zitian Huo,Yinxia Su,Yuting Dong,Yiyun Zheng,Qian Zhang,Yaqi Duan,Guoping Wang

Drug design, development and therapy 13:3559-3568 PubMed31686786

2019

Tanshinone I Inhibits IL-1β-Induced Apoptosis, Inflammation And Extracellular Matrix Degradation In Chondrocytes CHON-001 Cells And Attenuates Murine Osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Xipeng Wang,Jianbo Fan,Xiaomin Ding,Yuyu Sun,Zhiming Cui,Wei Liu

Pathology, research and practice 215:152442 PubMed31078342

2019

SOX11 promotes osteoarthritis through induction of TNF-α.

Applications

Unspecified application

Species

Unspecified reactive species

Shiping Xu,Jingcheng Yu,Zhirong Wang,Chunlin Ni,Long Xia,Tianyi Tang

The Journal of pathology 243:193-207 PubMed28707729

2017

SOX11 promotes invasive growth and ductal carcinoma in situ progression.

Applications

Unspecified application

Species

Unspecified reactive species

Erik Oliemuller,Naoko Kogata,Philip Bland,Divya Kriplani,Frances Daley,Syed Haider,Vandna Shah,Elinor J Sawyer,Beatrice A Howard
View all publications
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