AB191699

Anti-SOX17 antibody

Name: Anti-SOX17 antibody (ab191699) | Abcam
Brand: Abcam Limited
SKU: AB191699
Price: 535 USD
Availability: InStock
Rating: 1 (1 reviews)

(1 Review)

(8 Publications)

Rabbit Polyclonal SOX17 antibody. Suitable for WB and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Synthetic Peptide within Human SOX17.

View Alternative Names

Transcription factor SOX-17, SOX17

1 Images

Supplier Data

Western blot - Anti-SOX17 antibody (AB191699)

Lane 1:

Western blot - Anti-SOX17 antibody (ab191699) at 0.5 µg/mL

Lane 2:

Western blot - Anti-SOX17 antibody (ab191699) at 1 µg/mL

All lanes:

HepG2 cell lysate at 15 µg

Predicted band size: 44 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human SOX17. The exact immunogen used to generate this antibody is proprietary information.

Q9H6I2

Specificity

Predicted not cross-react with other SOX proteins.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Acts as a transcription regulator that binds target promoter DNA (PubMed : 33952808). Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal development of the definitive gut endoderm. Required for normal looping of the embryonic heart tube. Plays an important role in embryonic and postnatal vascular development, including development of arteries. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX18. Required for the generation and maintenance of fetal hematopoietic stem cells, and for fetal hematopoiesis. Probable transcriptional activator in the premeiotic germ cells.

See full target information SOX17

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Publications (8)

Recent publications for all applications. Explore the full list and refine your search

Circulation 151:299-317 PubMed39429196

2024

Arterial-Lymphatic-Like Endothelial Cells Appear in Hereditary Hemorrhagic Telangiectasia 2 and Contribute to Vascular Leakage and Arteriovenous Malformations.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Yang,Xiuju Wu,Yan Zhao,Daoqin Zhang,Li Zhang,Xinjiang Cai,Jaden Ji,Zheng Jing,Kristina I Boström,Yucheng Yao

The EMBO journal 40:e104729 PubMed33349972

2020

hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf.

Applications

Unspecified application

Species

Unspecified reactive species

Xue Wang,Changyun Ping,Puwen Tan,Chenguang Sun,Guang Liu,Tao Liu,Shuchun Yang,Yanmin Si,Lijun Zhao,Yongfei Hu,Yuyan Jia,Xiaoshuang Wang,Meili Zhang,Fang Wang,Dong Wang,Jia Yu,Yanni Ma,Yue Huang

Frontiers in immunology 11:1996 PubMed32903551

2020

Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime.

Applications

Unspecified application

Species

Unspecified reactive species

Zhe Zhang,Shuangshuang Lu,Louisa S Chard Dunmall,Zhizhong Wang,Zhenguo Cheng,Zhongxian Zhang,Wenli Yan,Yongchao Chu,Dongling Gao,Na Wang,Yang Li,Jiwei Wang,Yuenan Li,Yupei Ji,Danyang Shan,Keke Li,Panpan Wang,Yunshu Dong,Jianzeng Dong,Nick R Lemoine,Duanqing Pei,Lirong Zhang,Yaohe Wang

Molecular neurobiology 57:3969-3978 PubMed32632606

2020

Small Molecule Differentiate PDX1-Expressing Cells Derived from Human Endometrial Stem Cells on PAN Electrospun Nanofibrous Scaffold: Applications for the Treatment of Diabetes in Rat.

Applications

Unspecified application

Species

Unspecified reactive species

Saad Gooraninejad,Elham Hoveizi,Kiavash Hushmandi,Sina Gooraninejad,Seyed Reza Fatemi Tabatabaei

Journal of materials science. Materials in medicin 30:101 PubMed31473826

2019

Differentiation of endometrial stem cells into insulin-producing cells using signaling molecules and zinc oxide nanoparticles, and three-dimensional culture on nanofibrous scaffolds.

Applications

Unspecified application

Species

Unspecified reactive species

Elham Hoveizi,Tayebeh Mohammadi

Journal of cellular physiology 234:10196-10204 PubMed30387142

2018

Therapeutic potential of human mesenchymal stem cells derived beta cell precursors on a nanofibrous scaffold: An approach to treat diabetes mellitus.

Applications

Unspecified application

Species

Unspecified reactive species

Elham Hoveizi,Shima Tavakol

Cell death & disease 9:893 PubMed30166528

2018

SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency.

Applications

Unspecified application

Species

Unspecified reactive species

Ah-Young Kim,Eun-Mi Lee,Eun-Joo Lee,Jae-Hong Kim,Kyoungho Suk,Eunhye Lee,Keun Hur,Yean Ju Hong,Jeong Tae Do,SunYoung Park,Kyu-Shik Jeong

International journal of molecular medicine 38:1047-54 PubMed27513557

2016

5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1.

Applications

Species

Human

Wenli Li,Dan Wu,Ziyu Niu,Dalei Jiang,Huan Ma,Heming He,Xiuli Zuo,Xiangjun Xie,Yuanlong He

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SOX17 antibody

Western blot - Anti-SOX17 antibody (AB191699)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (8)

Product promise