Rabbit Recombinant Monoclonal SOX18 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications.
Images
![Western blot - Anti-SOX18 antibody [EPR2837(2)] (AB109194), expandable thumbnail](https://content.abcam.com/products/images/sox18-antibody-epr28372-ab109194--western-blot-img69339.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-SOX18 antibody [EPR2837(2)] (AB109194)")
Publications
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- The Journal of clinical investigation 131:2021SUMOylation promotes extracellular vesicle-mediated transmission of lncRNA ELNAT1 and lymph node metastasis in bladder cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChanghao Chen,Hanhao Zheng,Yuming Luo,Yao Kong,Mingjie An,Yuting Li,Wang He,Bowen Gao,Yue Zhao,Hao Huang,Jian Huang,Tianxin LinPubMed 33661764
- Bioscience reports 39:2019Down-regulation of SOX18 inhibits laryngeal carcinoma cell proliferation, migration, and invasion through JAK2/STAT3 signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYice Xu et. al.PubMed 31189744
- OncoTargets and therapy 11:8481-84902018Upregulation of SOX18 in colorectal cancer cells promotes proliferation and correlates with colorectal cancer risk.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZuohua Miao et. al.PubMed 30555240
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| ICC/IF | IP | Flow Cyt | WB | IHC-P | |
|---|---|---|---|---|---|
| Human | Not recommended | Not recommended | Not recommended | Tested | Not recommended |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
IP
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Flow Cyt
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers. Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17. Interaction with MEF2C enhances transcriptional activation. Besides, required for normal hair development.
Alternative names
Transcription factor SOX-18, SOX18
Recommended products
Rabbit Recombinant Monoclonal SOX18 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR2837(2)
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Stable for 12 months at -20°C
Notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Western blot - Anti-SOX18 antibody [EPR2837(2)] (ab109194), expandable thumbnail](https://content.abcam.com/products/images/sox18-antibody-epr28372-ab109194--western-blot-img69339.jpg "Western blot - Anti-SOX18 antibody [EPR2837(2)] (ab109194)")
Western blot - Anti-SOX18 antibody [EPR2837(2)] (ab109194)
All lanes: Western blot - Anti-SOX18 antibody [EPR2837(2)] (ab109194) at 1/1000 dilution
Lane 1: K562 cell lysate at 10 µg
Lane 2: Human stomach cell lysate at 10 µg
Lane 3: Jurkat cell lysate at 10 µg
Lane 4: HeLa cell lysate at 10 µg
SecondaryAll lanes: HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 41 kDa
Observed band size: 41 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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