AB54371

Anti-SOX22 antibody [86C2a]

Name: Anti-SOX22 antibody [86C2a] (ab54371) | Abcam
Brand: Abcam Limited
SKU: AB54371
Price: 510 USD
Availability: InStock

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(7 Publications)

Mouse Monoclonal SOX22 antibody. Suitable for WB and reacts with Recombinant fragment - Human samples. Cited in 7 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SOX12.

View Alternative Names

SOX22, SOX12, Transcription factor SOX-12, Protein SOX-22

1 Images

Unknown

Western blot - Anti-SOX22 antibody [86C2a] (AB54371)

All lanes:

Western blot - Anti-SOX22 antibody [86C2a] (ab54371)

All lanes:

immunised recombinant protein

Predicted band size: 34 kDa

Observed band size: 30 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

86C2a

Isotype

IgG2a

Carrier free

Applications

applications

Immunogen

Recombinant Fragment Protein within Human SOX12. The exact immunogen used to generate this antibody is proprietary information.

O15370

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant fragment - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

ab54371 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.

Storage buffer

pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 1% BSA, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.03% Tripotassium orthophosphate, 0.0225% Potassium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3' (By similarity). Acts as a transcriptional activator (By similarity). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Involved in the differentiation of naive CD4-positive T-cells into peripherally induced regulatory T (pT reg) cells under inflammatory conditions (By similarity). Binds to the promoter region of the FOXP3 gene and promotes its transcription, and might thereby contribute to pT reg cell differentiation in the spleen and lymph nodes during inflammation (By similarity). Plays a redundant role with SOX4 and SOX11 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).

See full target information SOX12

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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Cancer research 84:3574-3588 PubMed39047223

2024

FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoli Liu,Bonan Chen,Fuda Xie,Kit Yee Wong,Alvin H K Cheung,Jinglin Zhang,Qian Wu,Canbin Fang,Jintao Hu,Shouyu Wang,Dazhi Xu,Jianwu Chen,Yuzhi Wang,Chi Chun Wong,Huarong Chen,William K K Wu,Jun Yu,Michael W Y Chan,Chi Man Tsang,Kwok Wai Lo,Gary M K Tse,Ka-Fai To,Wei Kang

The Tohoku journal of experimental medicine 259:199-208 PubMed36517015

2022

MiR-423-5p Inhibition Exerts Protective Effects on Angiotensin II-Induced Cardiomyocyte Hypertrophy.

Applications

Unspecified application

Species

Unspecified reactive species

Meng Xu,Dongchen Liu,Xinyu Gao,Ziwen Wang,Linna Zhang,Hao Fan

Journal of ovarian research 14:161 PubMed34789303

2021

LncRNA MNX1-AS1 promotes ovarian cancer process via targeting the miR-744-5p/SOX12 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Shen,Mengmeng Lv,Yichen Fang,Jin Lu,Yuzhong Wu

Frontiers in oncology 11:711684 PubMed34745940

2021

LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network.

Applications

Unspecified application

Species

Unspecified reactive species

Duanyang Zhai,Tianfu Li,Runyi Ye,Jiong Bi,Xiaying Kuang,Yawei Shi,Nan Shao,Ying Lin

Cancer management and research 12:12403-12414 PubMed33293866

2020

TMPO-AS1, a Novel E2F1-Regulated lncRNA, Contributes to the Proliferation of Lung Adenocarcinoma Cells via Modulating miR-326/SOX12 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Lin Wei,Yugang Liu,Huijun Zhang,Yuefeng Ma,Zenghui Lu,Zhenning Gu,Chao Ding

Cancer letters 452:103-118 PubMed30922917

2019

Sex determining region Y-box 12 (SOX12) promotes gastric cancer metastasis by upregulating MMP7 and IGF1.

Applications

Unspecified application

Species

Unspecified reactive species

Feng Du,Weibo Feng,Sheng Chen,Shengda Wu,Tianyu Cao,Ting Yuan,Dean Tian,Yongzhan Nie,Kaichun Wu,Daiming Fan,Limin Xia

Oncology reports 40:3585-3592 PubMed30542724

2018

MicroRNA‑744 inhibits migration and invasion of hepatocellular carcinoma cells by targeting SOX12.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Zhang,Kai Liu,Songyang Liu,Bai Ji,Yahui Liu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SOX22 antibody [86C2a]

Western blot - Anti-SOX22 antibody [86C2a] (AB54371)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Applications

Immunogen

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (7)

Product promise