Mouse Monoclonal SOX4 antibody. Suitable for WB and reacts with Recombinant fragment - Human samples. Cited in 16 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SOX4.
Images
![Western blot - Anti-SOX4 antibody [154C4a] (AB70598), expandable thumbnail](https://content.abcam.com/products/images/sox4-antibody-154c4a-ab70598--western-blot-img96146.gif "Western blot - Anti-SOX4 antibody [154C4a] (AB70598)")
Publications
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- iScience 26:1062892023Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTing He,Shuai Wang,Shengnan Li,Huanming Shen,Lingfeng Hou,Yunjia Liu,Yixin Wei,Fuan Xie,Zhiming Zhang,Zehang Zhao,Chunli Mo,Huiling Guo,Qingsong Huang,Rui Zhang,Dongyan Shen,Boan LiPubMed 36968079
- Theranostics 12:7699-77162022SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHuanming Shen,Ting He,Shuai Wang,Lingfeng Hou,Yixin Wei,Yunjia Liu,Chunli Mo,Zehang Zhao,WeiXin You,Huiling Guo,Boan LiPubMed 36451857
- Cancer drug resistance (Alhambra, Calif.) 5:261-2702022Circular RNA drives resistance to anti-PD-1 immunotherapy by regulating the miR-30a-5p/SOX4 axis in non-small cell lung cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJing Wu,Meng-Xuan Zhu,Ke-Sang Li,Ling Peng,Peng-Fei ZhangPubMed 35800365
- Molecular therapy oncolytics 24:470-4852022Exosomal circSHKBP1 participates in non-small cell lung cancer progression through PKM2-mediated glycolysis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWenbiao Chen,Donge Tang,Junqi Lin,Xiaoming Huang,Shaoming Lin,Guanle Shen,Yong DaiPubMed 35229026
- The International journal of biological markers 36:10-202021Circ_0039411 promotes papillary thyroid carcinoma development through mediating the miR-423-5p/SOX4 signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaohui Wen,Jingyan Du,Xun WangPubMed 34738852
- Clinical and translational medicine 11:e6132021A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLu Wang,Jiahui Zhou,Chuan Zhang,Ranran Chen,Qingyang Sun,Peng Yang,Chaofan Peng,Yuqian Tan,Chi Jin,Tuo Wang,Jiangzhou Ji,Yueming SunPubMed 34709743
- Cancer management and research 13:7087-70992021TGF-β-MTA1-SMAD7-SMAD3-SOX4-EZH2 Signaling Axis Promotes Viability, Migration, Invasion and EMT of Hepatocellular Carcinoma Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKangjun Zhang,Taishi Fang,Yajie Shao,Yanhui WuPubMed 34531686
- Cancer management and research 13:6031-60432021Propofol Suppresses Gastric Cancer Progression by Regulating circPDSS1/miR-1324/SOX4 Axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLeyi Liu,Ting Dong,Jun ShengPubMed 34377022
- Cancer cell international 21:2842021LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYue Wu,Ting Wang,Lin Xia,Mei ZhangPubMed 34051810
- Oncology letters 22:5352021HLA complex group 11 is involved in colorectal carcinoma cisplatin resistance via the miR-214-5p/SOX4 axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJianping Xie,Jiaping Zhu,Jie Pang,Yaping MaPubMed 34079592
Key facts
- Isotype
- IgG2a
- Host species
- Mouse
- Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.1136% Disodium hydrogenorthophosphate, 0.03% Tripotassium orthophosphate, 0.0225% Potassium chloride, 0.0204% Potassium phosphate monobasic- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Recombinant Fragment Protein within Human SOX4. The exact immunogen used to generate this antibody is proprietary information. Database link Q06945
Consider this alternative
Reactivity data
Select an application| WB | |
|---|---|
| Recombinant fragment - Human | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Recombinant fragment - Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
4 products for Alternative Product
Target data
Function
Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed:30661772). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed:26291311).
Alternative names
Transcription factor SOX-4, SOX4
Recommended products
Mouse Monoclonal SOX4 antibody. Suitable for WB and reacts with Recombinant fragment - Human samples. Cited in 16 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SOX4.
Key facts
- Isotype
- IgG2a
- Host species
- Mouse
- Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.1136% Disodium hydrogenorthophosphate, 0.03% Tripotassium orthophosphate, 0.0225% Potassium chloride, 0.0204% Potassium phosphate monobasic- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Recombinant Fragment Protein within Human SOX4. The exact immunogen used to generate this antibody is proprietary information. Database link Q06945
- Clone number
- 154C4a
- Purification technique
- Affinity purification Protein G
- Concentration
- Purification notes
ab70598 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-SOX4 antibody [154C4a] (ab70598)
The molecular weight of the band on the western blot does not correspond to the molecular weight of the natural protein because only a fragment of the protein was used.
All lanes: Western blot - Anti-SOX4 antibody [154C4a] (ab70598)
All lanes: immunising recombinant protein
Predicted band size: 47 kDa
Observed band size: 38 kDa
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- Visit the general protocols
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