JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB243041

Anti-SOX4 antibody [CL5634]

1

(1 Review)

|

(10 Publications)

Mouse Monoclonal SOX4 antibody. Suitable for IHC-P, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 10 publications. Immunogen corresponding to Synthetic Peptide within Human SOX4 aa 300-350.

View Alternative Names

Transcription factor SOX-4, SOX4

7 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human endometrium tissue labelling SOX4 with ab243041 at 1/1000 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunocytochemistry/ Immunofluorescence - Anti-SOX4 antibody [CL5634] (AB243041)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-SOX4 antibody [CL5634] (AB243041)

Paraformaldehyde-fixed, Titon X-100 permeabilized SH-SY5Y (human neuroblastoma cell line from bone marrow) whole cell lysate labeling SOX4 (Green) using ab243041 at 10 μg/ml in ICC/IF. Microtubules visulized in red.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver tissue labelling SOX4 with ab243041 at 1/1000 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human glioma brain tumour tissue labelling SOX4 with ab243041 at 1/1000 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse dentate gyrus brain tissue labelling SOX4 with ab243041 at 1/1000 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat dentate gyrus brain tissue labelling SOX4 with ab243041 at 1/1000 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5634] (AB243041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of murine brain tissue labelling SOX4 with ab243041 at 1/1000 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

CL5634

Isotype

IgG2b

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Synthetic Peptide within Human SOX4 aa 300-350. The exact immunogen used to generate this antibody is proprietary information.

Q06945

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "2-10 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100</p>" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
Purified from TCS.
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed : 30661772). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed : 26291311).
See full target information SOX4

Publications (10)

Recent publications for all applications. Explore the full list and refine your search

Cell death and differentiation 32:447-465 PubMed39402212

2024

SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Shuai Wang,Ting He,Ya Luo,Kexin Ren,Huanming Shen,Lingfeng Hou,Yixin Wei,Tong Fu,Wenlong Xie,Peng Wang,Jie Hu,Yu Zhu,Zhengrong Huang,Qiyuan Li,Weihua Li,Huiling Guo,Boan Li

Communications biology 7:11 PubMed38172218

2024

Single-cell transcriptomics enable the characterization of local extension in retinoblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yaoming Liu,Wei Hu,Yanjie Xie,Junjie Tang,Huan Ma,Jinmiao Li,Jiahe Nie,Yinghao Wang,Yang Gao,Chao Cheng,Cheng Li,Yujun Ma,Shicai Su,Zhihui Zhang,Yuekun Bao,Yi Ren,Xinyue Wang,Fengyu Sun,Shengli Li,Rong Lu

Open medicine (Warsaw, Poland) 18:20230667 PubMed37251541

2023

miR-2053 inhibits the growth of ovarian cancer cells by downregulating SOX4.

Applications

Unspecified application

Species

Unspecified reactive species

Xin Huang,Wen Zhang,Xiumin Shen,Sai Ma,Lili Liu

Nature protocols 18:1930-1957 PubMed37045994

2023

Neural cell isolation from adult macaques for high-throughput analyses and neurosphere cultures.

Applications

Unspecified application

Species

Unspecified reactive species

Jia-Ru Wei,Dongchang Xiao,Lei Tang,Nana Xu,Ruifeng Liu,Yuhui Shen,Zihui Xu,Xuan Sang,Jian Ge,Mengqing Xiang,Sheng Liu

Anti-cancer drugs 34:155-165 PubMed36539368

2022

Circ-ABCC4 contributes to prostate cancer progression and radioresistance by mediating miR-1253/SOX4 cascade.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Yu,Hong Du,Changhai Sun

Bioengineered 13:2611-2622 PubMed35112991

2022

Circular RNA circ_0000518 promotes breast cancer progression through the microRNA-1225-3p/SRY-box transcription factor 4 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Kang Shujuan,Li Zhongxin,Ma Jingfang,Cui Zhili,Wei Wei,Qian Liu,Yan Li

Nature 598:205-213 PubMed34616060

2021

Single-cell epigenomics reveals mechanisms of human cortical development.

Applications

Unspecified application

Species

Unspecified reactive species

Ryan S Ziffra,Chang N Kim,Jayden M Ross,Amy Wilfert,Tychele N Turner,Maximilian Haeussler,Alex M Casella,Pawel F Przytycki,Kathleen C Keough,David Shin,Derek Bogdanoff,Anat Kreimer,Katherine S Pollard,Seth A Ament,Evan E Eichler,Nadav Ahituv,Tomasz J Nowakowski

Cancer management and research 13:6031-6043 PubMed34377022

2021

Propofol Suppresses Gastric Cancer Progression by Regulating circPDSS1/miR-1324/SOX4 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Leyi Liu,Ting Dong,Jun Sheng

Genome biology 22:156 PubMed34001209

2021

A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks.

Applications

Unspecified application

Species

Unspecified reactive species

Chongze Yuan,Haojie Chen,Shiqi Tu,Hsin-Yi Huang,Yunjian Pan,Xiuqi Gui,Muyu Kuang,Xuxia Shen,Qiang Zheng,Yang Zhang,Chao Cheng,Hui Hong,Xiaoting Tao,Yizhou Peng,Xingxin Yao,Feilong Meng,Hongbin Ji,Zhen Shao,Yihua Sun

Cell reports 30:3051-3066.e7 PubMed32130906

2020

Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development.

Applications

Unspecified application

Species

Unspecified reactive species

Ashley G Anderson,Ashwinikumar Kulkarni,Matthew Harper,Genevieve Konopka
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com