AB243739

Anti-SOX4 antibody [CL5665]

Name: Anti-SOX4 antibody [CL5665] (ab243739) | Abcam
Brand: Abcam Limited
SKU: AB243739
Price: 495 USD
Availability: InStock

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(10 Publications)

Mouse Monoclonal SOX4 antibody. Suitable for IHC-P, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 10 publications. Immunogen corresponding to Synthetic Peptide within Human SOX4 aa 300-350.

View Alternative Names

Transcription factor SOX-4, SOX4

7 Images

Immunocytochemistry/ Immunofluorescence - Anti-SOX4 antibody [CL5665] (AB243739)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-SOX4 antibody [CL5665] (AB243739)

PFA fixed, Triton X-100 permeabilized SH-SY5Y (Human neuroblastoma cell line from bone marrow) cells labeling SOX4 using ab243739 at 10 μg/ml (green) in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Formalin-fixed, paraffin-embedded human glioma tissue stained for SOX4 with ab243739 at a 1/1000 dilution in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Formalin-fixed, paraffin-embedded human liver stained for SOX4 with ab243739 at a 1/1000 dilution in immunohistochemical analysis. Absence of nuclear positivity in hepatocytes as expected.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Formalin-fixed, paraffin-embedded mouse forebrain tissue stained for SOX4 with ab243739 at a 1/1000 dilution in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Formalin-fixed, paraffin-embedded mouse forebrain tissue stained for SOX4 with ab243739 at a 1/1000 dilution in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Formalin-fixed, paraffin-embedded rat hippocampus tissue stained for SOX4 with ab243739 at a 1/1000 dilution in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Formalin-fixed, paraffin-embedded mouse hippocampus tissue stained for SOX4 with ab243739 at a 1/1000 dilution in immunohistochemical analysis.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

CL5665

Isotype

IgG1

Carrier free

Reacts with

Mouse, Rat, Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Synthetic Peptide within Human SOX4 aa 300-350. The exact immunogen used to generate this antibody is proprietary information.

Q06945

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "2-10 µg/mL", "ICCIF-species-notes": "Fixation/Permeabilization: PFA/Triton X-100" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Purification notes

Purified from TCS.

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed : 30661772). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed : 26291311).

See full target information SOX4

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Publications (10)

Recent publications for all applications. Explore the full list and refine your search

American journal of reproductive immunology (New York, N.Y. : 1989) 94:e70132 PubMed40815040

2025

ATP/P2X4 Regulates Inflammation and Oxidative Stress in Endometriosis Through NLRP3 Inflammasome-Dependent Mechanisms.

Applications

Unspecified application

Species

Unspecified reactive species

Tingting Wu,Yan Guo

Investigative ophthalmology & visual science 66:24 PubMed40402518

2025

SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Jiahe Nie,Junjie Tang,Zhihui Zhang,Hetian Sun,Xinyue Wang,Longxiang Wang,Meng Wang,Weifeng Huang,Yang Gao,Jinmiao Li,Chao Cheng,Shicai Su,Shuxia Chen,Siming Ai,Yuxiang Mao,Ping Zhang,Yaoming Liu,Rong Lu

Translational oncology 50:102120 PubMed39288695

2024

SOX4 promotes vascular abnormality in glioblastoma and is a novel target to improve drug delivery.

Applications

Unspecified application

Species

Unspecified reactive species

Kunhua Yao,Mingbiao Yang,Mi Shu,Tian Wang,Dan Gao,Liqi Zhou,Guangwei Wang,Zaiqi Zhang,Jiefu Tang

Clinical and experimental pharmacology & physiology 51:e13914 PubMed39139001

2024

Cancer-associated fibroblast-derived circFARP1 modulates non-small cell lung cancer invasion and metastasis through the circFARP1/miR-338-3p/SOX4 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Wailong Zou,Yulin Li,Jia Zhang,Rui Yang,Yaxin Yan,Xin Zhang,Lei Yan,Zhe Zhang,Xinjun Zhang,Jichao Chen

JOR spine 7:e1284 PubMed38249720

2024

Pain behavior and phenotype in a modified anterior lumbar disc puncture mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Yuming Huang,Linchuan Lei,Jian Zhu,Jinjian Zheng,Zemin Li,Hua Wang,Jianru Wang,Zhaomin Zheng

Communications biology 7:11 PubMed38172218

2024

Single-cell transcriptomics enable the characterization of local extension in retinoblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yaoming Liu,Wei Hu,Yanjie Xie,Junjie Tang,Huan Ma,Jinmiao Li,Jiahe Nie,Yinghao Wang,Yang Gao,Chao Cheng,Cheng Li,Yujun Ma,Shicai Su,Zhihui Zhang,Yuekun Bao,Yi Ren,Xinyue Wang,Fengyu Sun,Shengli Li,Rong Lu

Journal of orthopaedic surgery and research 18:809 PubMed37904207

2023

miR-3195 suppresses the malignant progression of osteosarcoma cells via targeting SOX4.

Applications

Unspecified application

Species

Unspecified reactive species

Jianwei Liang,Dandan Bao,Zhan Ye,Binhao Cao,Guojun Jin,Zhenyu Lu,Jianjun Chen

Journal of orthopaedic research : official publication of the Orthopaedic Research Society 42:172-182 PubMed37377113

2023

Acetylshikonin promoting PI3K/Akt pathway and inhibiting SOX4 expression to delay intervertebral disc degeneration and low back pain.

Applications

Unspecified application

Species

Unspecified reactive species

Yuming Huang,Linchuan Lei,Zhuoyang Zhao,Zemin Li,Hua Wang,Shunlun Chen,Jinjian Zheng,Guowei Jiang,Xingyu Guo,Jiamin Li,Jianru Wang,Zhaomin Zheng,Fan Chen

Open life sciences 17:393-400 PubMed35573654

2022

SOX4 promotes high-glucose-induced inflammation and angiogenesis of retinal endothelial cells by activating NF-κB signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Haifeng Wei,Quan Gu

Disease markers 2021:6256369 PubMed34616498

2021

E2F1-Induced lncRNA BAIAP2-AS1 Overexpression Contributes to the Malignant Progression of Hepatocellular Carcinoma via miR-361-3p/SOX4 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Yang,Hong Ge,De-Qing Li,Ai-Xia Xu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SOX4 antibody [CL5665]

Immunocytochemistry/ Immunofluorescence - Anti-SOX4 antibody [CL5665] (AB243739)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [CL5665] (AB243739)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (10)

Product promise