AB236557

Anti-SOX4 antibody [SOX4/2540]

Name: Anti-SOX4 antibody [SOX4/2540] (ab236557) | Abcam
Brand: Abcam Limited
SKU: AB236557

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(5 Publications)

Mouse Monoclonal SOX4 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SOX4.

View Alternative Names

Transcription factor SOX-4, SOX4

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [SOX4/2540] (AB236557)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [SOX4/2540] (AB236557)

Formalin-fixed, paraffin-embedded human colon carcinoma tissue stained for SOX4 using ab236557 at 2 μg/ml in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [SOX4/2540] (AB236557)

Formalin-fixed, paraffin-embedded human breast carcinoma tissue stained for SOX4 using ab236557 at 2 μg/ml in immunohistochemical analysis.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

SOX4/2540

Isotype

IgG2b

Light chain type

kappa

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Full Length Protein corresponding to Human SOX4.

Q06945

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Incubate with primary antibody for 30 minutes at RT.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A/G

Purification notes

Purified from bioreactor concentrate by Protein A/G.

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed : 30661772). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed : 26291311).

See full target information SOX4

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:7136 PubMed37932296

2023

FNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment.

Applications

Unspecified application

Species

Unspecified reactive species

Zongchao Sun,Likun Yang,Abdukahar Kiram,Jing Yang,Zhuangzhuang Yang,Liwei Xiao,Yujing Yin,Jing Liu,Yan Mao,Danxia Zhou,Hao Yu,Zheng Zhou,Dengqiu Xu,Yuhuan Jia,Chenyun Ding,Qiqi Guo,Hongwei Wang,Yan Li,Li Wang,Tingting Fu,Shijun Hu,Zhenji Gan

Medicine 100:e25028 PubMed33761659

2021

Clinicopathological significance of SOX4 and epithelial-mesenchymal transition markers in patients with laryngeal squamous cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Mingjie Zhang,Hui Li,Yuefeng Han,Mengjun Wang,Junjie Zhang,Shiyin Ma

OncoTargets and therapy 14:1589-1604 PubMed33688206

2021

An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Kunlun Chen,Pengfei Zhu,Yuan Liao,Lei Yan,Ruo Feng,Wenlong Zhai

Communications biology 3:778 PubMed33328604

2020

Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Baijun Dong,Juju Miao,Yanqing Wang,Wenqin Luo,Zhongzhong Ji,Huadong Lai,Man Zhang,Xiaomu Cheng,Jinming Wang,Yuxiang Fang,Helen He Zhu,Chee Wai Chua,Liancheng Fan,Yinjie Zhu,Jiahua Pan,Jia Wang,Wei Xue,Wei-Qiang Gao

Bioscience reports 40: PubMed31894841

2020

NORAD accelerates chemo-resistance of non-small-cell lung cancer via targeting at miR-129-1-3p/SOX4 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Qiang Huang,Shijiang Xing,Aiping Peng,Zhiwu Yu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SOX4 antibody [SOX4/2540]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [SOX4/2540] (AB236557)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX4 antibody [SOX4/2540] (AB236557)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

Product promise