AB221053

Anti-SOX8 antibody

Name: Anti-SOX8 antibody (ab221053) | Abcam
Brand: Abcam Limited
SKU: AB221053
Price: 645 USD
Availability: InStock

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(5 Publications)

Rabbit Polyclonal SOX8 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SOX8 aa 150-250.

View Alternative Names

Transcription factor SOX-8, SOX8

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-SOX8 antibody (AB221053)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-SOX8 antibody (AB221053)

Immunofluorescent analysis of PFA-fixed/Triton X-100 permeabilized RH30 cells labeling SOX8 with ab221053 at 4 μg/ml (green).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human SOX8 aa 150-250. The exact immunogen used to generate this antibody is proprietary information.

P57073

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcription factor that may play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity).

See full target information SOX8

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

BioMed research international 2022:9235837 PubMed36246971

2022

SOX8 Knockdown Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting the Notch Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongbo Du,Xiaobin Chen,Pingyu Zhu,Wei Sun,Qi Lv,Shulin Cheng,Xuesong Yang,Xiaodong Yu

Journal of cell science 135: PubMed34897463

2022

Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body.

Applications

Unspecified application

Species

Unspecified reactive species

Laasya Dhandapani,Marion C Salzer,Juan M Duran,Gabriele Zaffagnini,Cristian De Guirior,Maria Angeles Martínez-Zamora,Elvan Böke

Cellular and molecular gastroenterology and hepatology 12:873-889 PubMed34058415

2021

Polycomb Repressive Complex 2 Regulates Genes Necessary for Intestinal Microfold Cell (M Cell) Development.

Applications

Unspecified application

Species

Unspecified reactive species

Joel Johnson George,Mikko Oittinen,Laura Martin-Diaz,Veronika Zapilko,Sharif Iqbal,Terhi Rintakangas,Fábio Tadeu Arrojo Martins,Henri Niskanen,Pekka Katajisto,Minna U Kaikkonen,Keijo Viiri

Cellular and molecular gastroenterology and hepatology 12:489-506 PubMed33864900

2021

The Heteromeric Complex Formed by Dopamine Receptor D and CCR9 Leads the Gut Homing of CD4 T Cells Upon Inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Francisco Osorio-Barrios,Gemma Navarro,Javier Campos,Valentina Ugalde,Carolina Prado,Iu Raïch,Francisco Contreras,Ernesto López,Alexandra Espinoza,Alvaro Lladser,Rafael Franco,Rodrigo Pacheco

Theranostics 10:6928-6945 PubMed32550913

2020

Aurora-A/SOX8/FOXK1 signaling axis promotes chemoresistance via suppression of cell senescence and induction of glucose metabolism in ovarian cancer organoids and cells.

Applications

Unspecified application

Species

Unspecified reactive species

Huizhen Sun,Husheng Wang,Xue Wang,Yoichi Aoki,Xinjing Wang,Yufei Yang,Xi Cheng,Ziliang Wang,Xipeng Wang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SOX8 antibody

Immunocytochemistry/ Immunofluorescence - Anti-SOX8 antibody (AB221053)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

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Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise