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AB99408

Anti-SRCAP antibody

0

(1 Review)

|

(5 Publications )

Goat Polyclonal SRCAP antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human SRCAP aa 700 to C-terminus.
1 Images
Immunocytochemistry/ Immunofluorescence - Anti-SRCAP antibody (AB99408)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-SRCAP antibody (AB99408)

Immunocytochemistry/Immunofluorescence analysis of A431 cells labelling SRCAP with ab99408 at 10 μg/ml. Cells were paraformaldehyde fixed and permeabilized with 0.15% triton. Primary antibody icubation was for 1 hour followed by incubation with an Alexa Fluor® 488-conjugated secondary antibody at 2 μg/ml. DAPI nuclear counterstain was used.

Negative control : Unimmunized goat IgG (10 μg/ml) followed by an Alexa Fluor® 488-conjugated secondary antibody (2 μg/ml).

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Synthetic Peptide within Human SRCAP aa 700 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q6ZRS2

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Dog": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab99408 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts both as a chromatin remodeler and transcription coregulator. Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes expression through chromatin remodeling (PubMed : 16634648, PubMed : 17617668). Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription (PubMed : 10347196, PubMed : 11522779, PubMed : 14500758, PubMed : 16024792).
See full target information SRCAP

Alternative Names

KIAA0309, SRCAP, Chromatin remodeling protein SRCAP, Domino homolog 2, Snf2-related CBP activator
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

EMBO reports 23:e54128 PubMed35876654

2022

LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoting Liu,Jianxiong Chen,Sijing Zhang,Xunhua Liu,Xiaoli Long,Jiawen Lan,Miao Zhou,Lin Zheng,Jun Zhou

Cells 9: PubMed32708675

2020

VPS72/YL1-Mediated H2A.Z Deposition Is Required for Nuclear Reassembly after Mitosis.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel Moreno-Andrés,Hideki Yokoyama,Anja Scheufen,Guillaume Holzer,Hongqi Lue,Anna Katharina Schellhaus,Marion Weberruss,Masatoshi Takagi,Wolfram Antonin

Cell 178:1421-1436.e24 PubMed31491386

2019

Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Rachel S Greenberg,Hannah K Long,Tomek Swigut,Joanna Wysocka

Cell 172:993-1006.e13 PubMed29456083

2018

Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming.

Applications

Unspecified application

Species

Unspecified reactive species

Patrick J Murphy,Shan Fu Wu,Cody R James,Candice L Wike,Bradley R Cairns

Nucleic acids research 42:1016-25 PubMed24163101

2013

Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation.

Applications

WB

Species

Human

Jungmin Seo,Kwoneel Kim,Dong-Yeop Chang,Ho-Bum Kang,Eui-Cheol Shin,Jongbum Kwon,Jung Kyoon Choi
View all publications
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Product promise

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