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AB172215

Anti-SSX4 antibody

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(1 Publication)

Mouse Polyclonal SSX4 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SSX4.

View Alternative Names

SSX4A, SSX4B, SSX4, Protein SSX4, Cancer/testis antigen 5.4, CT5.4

1 Images
Western blot - Anti-SSX4 antibody (AB172215)
  • WB

Supplier Data

Western blot - Anti-SSX4 antibody (AB172215)

All lanes:

Western blot - Anti-SSX4 antibody (ab172215) at 1 µg/mL

Lane 1:

SSX4 transfected 293T cell lysate at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Secondary

All lanes:

Goat Anti-Mouse IgG at 1/2500 dilution

Predicted band size: 22 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human SSX4.

O60224

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SSX4 also known as Synovial Sarcoma X breakpoint 4 is a protein belonging to the SSX family of proteins. This protein has a molecular weight of approximately 22 kDa. It is typically expressed in testicular tissues but also appears in various tumors. Like other SSX proteins SSX4 contains a characteristic KRAB domain suggesting its involvement in transcriptional regulation processes.
Biological function summary

The function of SSX4 extends to the regulation of transcription. It may act as a transcriptional repressor and participate in chromatin remodeling. SSX4 can form part of larger protein complexes influencing transcriptional activity in the cells where it is expressed. In cancer cells this protein's transcriptional regulatory role might contribute to abnormal cell growth through altered gene expression patterns.

Pathways

The SSX4 protein interacts within cellular pathways associated with tumorigenesis and transcriptional regulation. It is connected to the MAPK signaling pathway impacting cellular proliferation and survival. SSX4 may have interactions with proteins in the MAPK pathway such as RAF and ERK which mediate signal transduction processes involved in cell growth and differentiation.

The abnormal expression of SSX4 is linked primarily to synovial sarcoma a type of soft tissue cancer. SSX4 when involved in translocations can create fusion proteins like SSX4-SS18 that alter normal cellular pathways leading to tumorigenesis. This protein is also investigated in contexts of other cancers potentially interacting with proteins like SSX2 through shared pathway mechanisms in cancerous growth.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Could act as a modulator of transcription.
See full target information SSX4
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Oncotarget 7:49677-49687 PubMed27331623

2016

The "melanoma-enriched" microRNA miR-4731-5p acts as a tumour suppressor.

Applications

Unspecified application

Species

Unspecified reactive species

Mitchell S Stark,Lisa N Tom,Glen M Boyle,Vanessa F Bonazzi,H Peter Soyer,Adrian C Herington,Pamela M Pollock,Nicholas K Hayward
View all publications
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