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AB229993

Anti-STARD9 antibody

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(1 Publication)

Rabbit Polyclonal STARD9 antibody. Suitable for WB, IHC-P and reacts with Recombinant fragment - Human, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human STARD9 aa 1950-2200.

View Alternative Names

KIAA1300, STARD9, StAR-related lipid transfer protein 9, START domain-containing protein 9, StARD9

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STARD9 antibody (AB229993)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STARD9 antibody (AB229993)

Paraffin-embedded human colon cancer tissue stained for STARD9 using ab229993 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-STARD9 antibody (AB229993)
  • WB

Supplier Data

Western blot - Anti-STARD9 antibody (AB229993)

All lanes:

Western blot - Anti-STARD9 antibody (ab229993) at 1/500 dilution

Lane 1:

Recombinant STARD9 protein at 0.08 µg

Lane 2:

Recombinant STARD9 protein at 0.04 µg

Lane 3:

Recombinant STARD9 protein at 0.02 µg

Lane 4:

Recombinant STARD9 protein at 0.01 µg

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 507 kDa

Observed band size: 54 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human STARD9 aa 1950-2200. The exact immunogen used to generate this antibody is proprietary information.

Q9P2P6

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Recombinant fragment - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

STARD9 also known as StAR-related lipid transfer domain-containing protein 9 is a large protein with a molecular mass of approximately 560 kDa. This protein plays a role in cellular processes by acting as a kinesin-like motor protein. It is expressed in a variety of tissues with significant expression levels observed in the testes and brain. STARD9 is associated with microtubule organizing centers regulating mitotic spindle assembly and stability during cell division.
Biological function summary

STARD9 influences important aspects of cell division mechanics. As a component of the mitotic spindle machinery it interacts with microtubule dynamics to ensure accurate chromosomal alignment and segregation. STARD9's role within the kinesin superfamily facilitates its participation in the transport of organelles and vesicles along the microtubules affecting cellular distribution mechanisms.

Pathways

The protein engages with several microtubule-associated pathways. STARD9 is involved in the mitotic spindle checkpoint ensuring proper spindle architecture and function during mitosis. It associates with proteins like dynein and the augmin complex which are key players in microtubule stabilization and spindle organization. This interaction highlights its involvement in cell cycle control pathways.

STARD9 has connections to various cancer types. Disruption or aberrant expression of STARD9 may lead to improper cell division contributing to tumorigenesis. It is associated with proteins such as p53 known for their roles in controlling cell cycle arrest and apoptosis highlighting its potential impact on cancer progression. The stability of STARD9 function is critical as its dysregulation might relate to neurodegenerative diseases where altered microtubule dynamics play a role.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM).
See full target information STARD9

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in veterinary science 7:570593 PubMed33240950

2020

Effects of Probiotics BaSC06 on Intestinal Digestion and Absorption, Antioxidant Capacity, Microbiota Composition, and Macrophage Polarization in Pigs for Fattening.

Applications

Unspecified application

Species

Unspecified reactive species

Xuefang Cao,Li Tang,Zihan Zeng,Baikui Wang,Yuanhao Zhou,Qi Wang,Peng Zou,Weifen Li
View all publications

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