Rabbit Polyclonal START domain containing 7 antibody. Suitable for WB and reacts with Human samples.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine- Form
- Liquid
- Clonality
- Polyclonal
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
| Mouse | Predicted |
| Rat | Predicted |
| Cow | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Cow | Dilution info - | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
May play a protective role in mucosal tissues by preventing exaggerated allergic responses.
Alternative names
GTT1, STARD7, Gestational trophoblastic tumor protein 1, START domain-containing protein 7, StARD7
Recommended products
Rabbit Polyclonal START domain containing 7 antibody. Suitable for WB and reacts with Human samples.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine- Form
- Liquid
- Clonality
- Polyclonal
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
START domain containing 7 (STARD7) also known as StAR-related lipid transfer protein 7 is a protein involved in lipid transfer and metabolism. It is approximately 37 kDa in mass. STARD7 facilitates the movement of phospholipids between membranes playing a role in maintaining cellular lipid balance. The protein is broadly expressed in various tissues including liver kidney and the gastrointestinal tract indicating its widespread functional importance in the body.
- Biological function summary
The lipid transport function of STARD7 contributes to maintaining membrane integrity and cellular homeostasis. It is involved in intracellular lipid signaling pathways impacting diverse cellular processes. STARD7 does not form a part of large protein complexes but functions alongside other lipid transfer proteins helping to regulate levels of important lipids in the cell. Its activity impacts cellular processes that rely on dynamic membrane composition and signaling lipid availability.
- Pathways
STARD7 participates in the lipid signaling and transport pathways. It acts within the phosphatidylcholine transfer pathway cooperating with phosphatidylcholine transfer proteins. This activity links STARD7 closely with lipid metabolism pathways and phospholipid transfer cycles that are central to cellular energy homeostasis and membrane dynamics. These pathways often connect with broader metabolic processes influenced by related proteins such as STARD5.
- Associated diseases and disorders
Dysfunction of STARD7 associates with metabolic syndromes and gastrointestinal diseases. Altered lipid transfer due to problems in STARD7 expression or function has implications in obesity-related metabolic disruption. It is also linked to inflammatory bowel diseases where lipid homeostasis plays a part in intestinal inflammation and immune responses. In these conditions STARD7 interacts with proteins involved in lipid metabolism and inflammatory signaling such as LXR receptors which further influence disease progression and patient outcomes.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
Western blot - Anti-START domain containing 7 antibody (ab101525)
10% SDS PAGE
Note: the lower band observed corresponds to the expected band size (~35 kDa) for the NCBI accession (AAH07894) and the unreviewed UniProt/TrEMBL protein (A8K575).
The band observed in the middle of the gel corresponds to the expected band size (~43 kDa) for the reviewed UniProt protein (Q9NQZ5).All lanes: Western blot - Anti-START domain containing 7 antibody (ab101525) at 1/1000 dilution
All lanes: Jurkat whole cell lysate at 30 µg
Predicted band size: 43 kDa
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