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AB221569

Anti-START domain containing 7 antibody

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(1 Publication)

Rabbit Polyclonal START domain containing 7 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human STARD7 aa 250 to C-terminus.

View Alternative Names

GTT1, STARD7, Gestational trophoblastic tumor protein 1, START domain-containing protein 7, StARD7

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-START domain containing 7 antibody (AB221569)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-START domain containing 7 antibody (AB221569)

PFA-fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells stained for START domain containing 7 (green) using ab221569 at 4 μg/ml in ICC/IF.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human STARD7 aa 250 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9NQZ5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

START domain containing 7 (STARD7) also known as StAR-related lipid transfer protein 7 is a protein involved in lipid transfer and metabolism. It is approximately 37 kDa in mass. STARD7 facilitates the movement of phospholipids between membranes playing a role in maintaining cellular lipid balance. The protein is broadly expressed in various tissues including liver kidney and the gastrointestinal tract indicating its widespread functional importance in the body.
Biological function summary

The lipid transport function of STARD7 contributes to maintaining membrane integrity and cellular homeostasis. It is involved in intracellular lipid signaling pathways impacting diverse cellular processes. STARD7 does not form a part of large protein complexes but functions alongside other lipid transfer proteins helping to regulate levels of important lipids in the cell. Its activity impacts cellular processes that rely on dynamic membrane composition and signaling lipid availability.

Pathways

STARD7 participates in the lipid signaling and transport pathways. It acts within the phosphatidylcholine transfer pathway cooperating with phosphatidylcholine transfer proteins. This activity links STARD7 closely with lipid metabolism pathways and phospholipid transfer cycles that are central to cellular energy homeostasis and membrane dynamics. These pathways often connect with broader metabolic processes influenced by related proteins such as STARD5.

Dysfunction of STARD7 associates with metabolic syndromes and gastrointestinal diseases. Altered lipid transfer due to problems in STARD7 expression or function has implications in obesity-related metabolic disruption. It is also linked to inflammatory bowel diseases where lipid homeostasis plays a part in intestinal inflammation and immune responses. In these conditions STARD7 interacts with proteins involved in lipid metabolism and inflammatory signaling such as LXR receptors which further influence disease progression and patient outcomes.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May play a protective role in mucosal tissues by preventing exaggerated allergic responses.
See full target information STARD7
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Translational oncology 26:101562 PubMed36228410

2022

ARNTL2 is an indicator of poor prognosis, promotes epithelial-to-mesenchymal transition and inhibits ferroptosis in lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Huan Zhang,Guangyao Shan,Xing Jin,Xiangyang Yu,GuoShu Bi,Mingxiang Feng,Hao Wang,Miao Lin,Cheng Zhan,Qun Wang,Ming Li
View all publications
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Product promise

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