Anti-STAT6 (phospho Y641) antibody
5
(12 Reviews)
|
(45 Publications)
Rabbit Polyclonal STAT6 phospho Y641 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 45 publications. Immunogen corresponding to Synthetic Peptide within Human STAT6 phospho Y641.
View Alternative Names
Signal transducer and activator of transcription 6, IL-4 Stat, STAT6
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STAT6 (phospho Y641) antibody (AB28829)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling STAT6 (phospho Y641) with ab28829. Right pane - blocked with the phospho peptide.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STAT6 (phospho Y641) antibody (AB28829)
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-STAT6 (phospho Y641) antibody (ab28829) at 1/100 dilution.
- IHC-P
AbReview7347****
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STAT6 (phospho Y641) antibody (AB28829)
ab28829 at 1/100 staining mouse lung tissue sections by IHC-P. The tissue was formaldehyde fixed and blocked with serum. A heat mediated antigen retrieval step was performed prior to incubation with the antibody. ab6720 (Goat polyclonal to Rabbit IgG H&L (biotin)) was used as the secondary antibody.
This image is courtesy of an anonymous Abreview
- WB
Supplier Data
Western blot - Anti-STAT6 (phospho Y641) antibody (AB28829)
Loading control is Actin
Lanes 1 - 2:
STAT6 antibody
Lanes 3 - 4:
Western blot - Anti-STAT6 (phospho Y641) antibody (ab28829) at 1/1000 dilution
Lanes 1 and 3:
K562 cells treated with 100 ng/mL IL4 at 20 µg
Lanes 2 and 4:
K562 untreated cells at 20 µg
Secondary
All lanes:
Dylight 800 secondary antibody at 1/10000 dilution
Predicted band size: 94 kDa
false
- WB
Supplier Data
Western blot - Anti-STAT6 (phospho Y641) antibody (AB28829)
Western blot analysis of lysates from HeLa cells treated with IL-4, using STAT6 (Phospho-Tyr641) Antibody. The lane on the right is blocked with the phospho peptide.
All lanes:
Western blot - Anti-STAT6 (phospho Y641) antibody (ab28829)
Predicted band size: 94 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
STAT6 plays a central role in the development and function of Th2 cells a subset of T helper cells. The protein controls genes linked to the immune response and inflammation such as IL-4 and IL-13 by binding to specific DNA sequences as part of the transcriptional complex. These processes are critical for antibody class switching in B cells and also for regulating the differentiation of T cells which are processes important in defending against parasitic infections and are linked to allergies.
Pathways
STAT6 functions mainly in the JAK-STAT signaling pathway a pathway important for transmitting information from chemical signals outside cells to the cell nucleus resulting in DNA transcription. Within this pathway STAT6 works closely with JAK1 and JAK3 kinases which phosphorylate STAT6 enabling its activation. The protein also connects with other members of the STAT family like STAT1 and STAT3 during overlapping signaling processes.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Publications (45)
Recent publications for all applications. Explore the full list and refine your search
iScience 28:113517 PubMed41031375
2025
Applications
Unspecified application
Species
Unspecified reactive species
Cell reports 44:116342 PubMed41004340
2025
Applications
Unspecified application
Species
Unspecified reactive species
Molecular cancer 24:34 PubMed39876004
2025
Applications
Unspecified application
Species
Unspecified reactive species
Nature immunology 24:1654-1670 PubMed37667051
2023
Applications
Unspecified application
Species
Unspecified reactive species
Science advances 8:eabo4363 PubMed35984890
2022
Applications
Unspecified application
Species
Unspecified reactive species
Molecular systems biology 18:e10855 PubMed35959629
2022
Applications
Unspecified application
Species
Unspecified reactive species
International journal of immunopathology and pharmacology 36:3946320221109529 PubMed35726645
2022
Applications
Unspecified application
Species
Unspecified reactive species
Cellular and molecular gastroenterology and hepatology 13:1449-1467 PubMed35108658
2022
Applications
Unspecified application
Species
Unspecified reactive species
Molecular oncology 16:2214-2234 PubMed34861103
2021
Applications
Unspecified application
Species
Unspecified reactive species
Proceedings of the National Academy of Sciences of the United States of America 118: PubMed34521750
2021
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com