AB263947

Anti-STAT6 (phospho Y641) antibody [EPR22599-78]

Name: Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947) | Abcam
Brand: Abcam Limited
SKU: AB263947
Price: 390 USD
Availability: InStock
Rating: 5 (1 reviews)

BOND RX™ Validated
RabMAb
Recombinant
20ul selling size
What is this?

(1 Review)

(45 Publications)

Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947) is a rabbit monoclonal antibody detecting STAT6 in Western Blot, Flow Cytometry (Intra), IP, Dot Blot. Suitable for Human, Mouse, Rat.

- Biophysical QC for unrivalled batch-batch consistency
- Over 20 publications

View Alternative Names

Signal transducer and transcription activator 6, Stat6

11 Images

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Intracellular flow cytometric analysis of 4% paraformaldehyde fixed 90% methanol permeabilized Daudi (Human Burkitt's lymphoma lymphoblast) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min (Red)/Untreated control (Green) cells labelling STAT6 (phospho Y641) with ab263947 at 1/500 dilution (Red) compared with a Rabbit monoclonal IgG (ab172730)isotype control (black)and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). A Goat anti rabbit IgG (Alexa Fluor^® 488, ab150077) at 1/2000 dilution was used as the secondary antibody.

STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Intracellular flow cytometric analysis of 4% paraformaldehyde fixed 90% methanol permeabilized Daudi (Human Burkitt's lymphoma lymphoblast) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min (Red)/Untreated control (Green) cells labelling STAT6 (phospho Y641) with ab263947 at 1/500 dilution (Red) compared with a Rabbit monoclonal IgG (ab172730)isotype control (black)and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). A Goat anti rabbit IgG (Alexa Fluor® 488, ab150077) at 1/2000 dilution was used as the secondary antibody. STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Unknown

Immunoprecipitation - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

STAT6 (phospho Y641) was immunoprecipitated from 0.35 mg Daudi (Human Burkitt's lymphoma lymphoblast) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate 10ug with ab263947 at 1 : 30 dilution (2ug in 0.35mg lysates). Western blot was performed on the immunoprecipitate using ab263947 at 1 : 1000 dilution. VeriBlot for IP Detection Reagent (HRP) (ab131366) was used at 1 : 5000 dilution.

Lane 1 : Daudi (Human Burkitt's lymphoma lymphoblast) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate 10ug

Lane 2 : ab263947 IP in Daudi was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate

Lane 3 : Rabbit monoclonal IgG (ab172730) instead of ab263947 in Daudi was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate

Blocking and dilution buffer and concentration : 5% NFDM/TBST.

STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Exposure time : 1 min

All lanes:

Immunoprecipitation - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947)

Predicted band size: 94 kDa

false

Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Intracellular flow cytometric analysis of 4% paraformaldehyde fixed 90% methanol permeabilized RAW 264.7 (Mouse Abelson murine leukemia virus-induced tumor macrophage) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min (Red) / Untreated control (Green) cells labelling STAT6 (phospho Y641) with ab263947 at 1/500 dilution (Red) compared with a Rabbit monoclonal IgG (ab172730) isotype control (Black)and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). A Goat anti rabbit IgG (Alexa Fluor^® 488, ab150077) at 1/2000 dilution was used as the secondary antibody.

STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Intracellular flow cytometric analysis of 4% paraformaldehyde fixed 90% methanol permeabilized RAW 264.7 (Mouse Abelson murine leukemia virus-induced tumor macrophage) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min (Red) / Untreated control (Green) cells labelling STAT6 (phospho Y641) with ab263947 at 1/500 dilution (Red) compared with a Rabbit monoclonal IgG (ab172730) isotype control (Black)and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). A Goat anti rabbit IgG (Alexa Fluor® 488, ab150077) at 1/2000 dilution was used as the secondary antibody. STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Unknown

Immunoprecipitation - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

STAT6 (phospho Y641) was immunoprecipitated from 0.35 mg RAW 264.7 (Mouse Abelson murine leukemia virus-induced tumor macrophage) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate 10ug with ab263947 at 1 : 30 dilution (2ug in 0.35mg lysates). Western blot was performed on the immunoprecipitate using ab263947 at 1 : 1000 dilution. VeriBlot for IP Detection Reagent (HRP) (ab131366) was used at 1 : 5000 dilution. Lane 1 : RAW 264.7 (Mouse Abelson murine leukemia virus-induced tumor macrophage) was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate 10ug

Lane 2 : ab263947 IP in RAW 264.7 was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate

Lane 3 : Rabbit monoclonal IgG (ab172730) instead of ab263947 in RAW 264.7 was serum starved for 24h, then treated with 100ng/ml IL-4 for 15min whole cell lysate

Blocking and dilution buffer and concentration : 5% NFDM/TBST.

Exposure time : 2 min

All lanes:

Immunoprecipitation - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947)

Predicted band size: 94 kDa

false

Lab

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Blocking and diluting buffer and concentration : 5% NFDM/TBST

Phosphorylation of STAT6 at Y641 can be induced by IL-4 treatment (PMID : 21411736,15044251) This antibody recognizes three isoforms of STAT6, isoform 1 (110 kDa), isoform 2 (75 kDa), isoform 3 (81 kDa), which is consistent with the Uniprot annotation.
STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Exposure time : 15 seconds

All lanes:

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947) at 1/5000 dilution

Lane 1:

Daudi (human Burkitts lymphoma lymphoblast) serum starved for 24 hours, whole cell lysate at 10 µg

Lane 2:

Daudi serum starved for 24 hours, then treated with 100 ng/ml IL-4 for 15 minutes, whole cell lysate 10 ug

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 94 kDa

Observed band size: 110 kDa,75 kDa,81 kDa

false

Lab

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Blocking and diluting buffer and concentration : 5% NFDM/TBST

Phosphorylation of STAT6 at Y641 can be induced by IL-4 treatment (PMID : 21411736,15044251) The molecular weight observed is consistent with what has been described in the literature (PMID : 24708771).

STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Exposure time : 37 seconds

All lanes:

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947) at 1/5000 dilution

Lane 1:

2.4G2 (rat B cell lymphoma B lymphocyte) serum starved for 24 hours, whole cell lysate at 10 µg

Lane 2:

2.4G2 serum starved for 24 hours, then treated with 100 ng/ml rIL-4 for 15 minutes, whole cell lysate 10 ug

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 94 kDa

Observed band size: 110 kDa,94 kDa

false

Lab

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Blocking and diluting buffer and concentration : 5% NFDM/TBST

Phosphorylation of STAT6 at Y641 can be induced by IL-4 treatment (PMID : 21411736,15044251) The molecular weight observed is consistent with what has been described in the literature (PMID : 24708771).

STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

Exposure time : 15 seconds

All lanes:

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947) at 1/1000 dilution

Lane 1:

RAW264.7 (mouse Abelson murine leukemia virus-induced tumor macrophage) serum starved for 24 hours, whole cell lysate at 10 µg

Lane 2:

RAW264.7 serum starved for 24 hours, then treated with 100 ng/ml mIL-4 for 15 minutes, whole cell lysate 10 ug

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 94 kDa

Observed band size: 110 kDa,94 kDa

false

Supplier Data

Dot Blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Dot blot analysis of STAT6 (phospho Y641) peptide (Lane 1 STAT6 non-phospho peptide peptide (Lane 2), labelling STAT 6 (pY641) with purified ab263947 at a dilution of 1/1000. ab97051 (Peroxidase conjugated goat anti-rabbit IgG (H+L)) was used as the secondary antibody at a dilution of 1/100000.

Blocking and dilution buffer : 5% NFDM/TBST.

Exposure time : 26 seconds.

CiteAb

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

STAT6 (phospho Y641) western blot using anti-STAT6 (phospho Y641) antibody [EPR22599-78] ab263947. Publication image and figure legend from Zeng, B., Wang, D., et al., 2020, Nutrients, PubMed 32911830.

ab263947 was used in this publication in western blot. This may not be the same as the application(s) guaranteed by Abcam. For a full list of applications guaranteed by Abcam for ab263947 please see the product overview.

Effect of SPI on JAK1-STAT6 signaling and TGFβ levels in mouse ileum tissue. (A) qRT-PCR analysis of Jak1, Stat6, Tgfb1, and Tgfb2 mRNA expression levels in mouse ileum tissue (normalized against Actb (β-actin); n = 8). (B) Western blot analysis of JAK1, p-JAK1, STAT6, p-STAT6, pIgR, and TGFβ1 protein levels in mouse ileum tissue (n = 6). (C) The statistical analyses of the Western blot results. Results are normalized to β-actin (n = 6). All data are presented as means ± SEM. NS, not significant (p > 0.05); * p < 0.05; ** p < 0.01. Statistical significance was calculated using t-tests.

false

Carrier free

Anti-STAT6 (phospho Y641) antibody [EPR22599-78] - BSA and Azide free
775 Alexa Fluor® 750

Alexa Fluor® 750 Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
578 PE

PE Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
660 APC

APC Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
HRP

HRP Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
665 Alexa Fluor® 647

Alexa Fluor® 647 Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
617 Alexa Fluor® 594

Alexa Fluor® 594 Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
565 Alexa Fluor® 555

Alexa Fluor® 555 Anti-STAT6 (phospho Y641) antibody [EPR22599-78]
603 Alexa Fluor® 568

Alexa Fluor® 568 Anti-STAT6 (phospho Y641) antibody [EPR22599-78]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR22599-78

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

IP, Dot, Flow Cyt (Intra), WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

STAT6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13.

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Reactivity data

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However, its expression is markedly upregulated in pathological states, including inflammatory responses and oncogenic activation (PMID: 36884218 ).", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/500", "FlowCytIntra-species-notes": "" }, "Mouse": { "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/30", "IP-species-notes": "", "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "Dot-species-checked": "guaranteed", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "p-STAT6 expression is typically undetectable or present at very low levels in healthy tissue lysates (e.g., kidney, lung, and skin) under physiological conditions (PMID: 34831280; PMID: 22401596; PMID: 24955743; PMID: 36629780). However, its expression is markedly upregulated in pathological states, including inflammatory responses and oncogenic activation (PMID: 36884218 ).", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Rat": { "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "Dot-species-checked": "guaranteed", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "p-STAT6 expression is typically undetectable or present at very low levels in healthy tissue lysates (e.g., kidney, lung, and skin) under physiological conditions (PMID: 34831280; PMID: 22401596; PMID: 24955743; PMID: 36629780). However, its expression is markedly upregulated in pathological states, including inflammatory responses and oncogenic activation (PMID: 36884218 ).", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Synthetic peptide": { "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "Dot-species-checked": "testedAndGuaranteed", "Dot-species-dilution-info": "1/1000", "Dot-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "notRecommended", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" } } }

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Product details

What is this antibody validated in?
Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (ab263947) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Dot Blot in Human, Mouse, Rat samples.

What is the molecular weight of STAT6?
Anti-STAT6 (phospho Y641) [EPR22599-78] (ab263947) specifically detects a band for STAT6 (UniProt: P52633) at a molecular weight of 94kDa.

Trusted by the scientific community
Anti-STAT6 (phospho Y641) [EPR22599-78] (ab263947) was first used in a scientific publication in 2019 and has been cited over 20 times in peer-reviewed journals.

Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

Other related products
We have a range of other formats of antibody clone [EPR22599-78] also available for your convenience: ab263947, Carrier free - ab263950, PE - ab305802, APC - ab305803, HRP - ab305804, Alkaline Phosphatase - ab308655, Alexa Fluor^® 488 - ab309630, Alexa Fluor^® 647 - ab309996, Alexa Fluor^® 594 - ab310359, Alexa Fluor^® 555 - ab311881, Alexa Fluor^® 568 - ab312350, Alexa Fluor^® 750 - ab321521

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

STAT6 also known as Signal Transducer and Activator of Transcription 6 is a transcription factor with a mass of around 94 kDa. This protein is an important component in the signaling pathways that respond to cytokines especially those of the IL-4 and IL-13 receptors. STAT6 mainly expresses in immune cells including T cells B cells and macrophages. It exists in the cytoplasm until the cytokine stimulation prompts its phosphorylation and translocation to the nucleus where it influences gene expression.

Biological function summary

STAT6 plays a central role in the development and function of Th2 cells a subset of T helper cells. The protein controls genes linked to the immune response and inflammation such as IL-4 and IL-13 by binding to specific DNA sequences as part of the transcriptional complex. These processes are critical for antibody class switching in B cells and also for regulating the differentiation of T cells which are processes important in defending against parasitic infections and are linked to allergies.

Pathways

STAT6 functions mainly in the JAK-STAT signaling pathway a pathway important for transmitting information from chemical signals outside cells to the cell nucleus resulting in DNA transcription. Within this pathway STAT6 works closely with JAK1 and JAK3 kinases which phosphorylate STAT6 enabling its activation. The protein also connects with other members of the STAT family like STAT1 and STAT3 during overlapping signaling processes.

STAT6 has associations with asthma and certain types of cancer such as colorectal cancer. In asthma STAT6 influences the production of IgE and eosinophilic inflammation often connected to allergic responses. Meanwhile STAT6 promotes tumorigenesis in some cancers by regulating genes responsible for cell survival and proliferation. It connects with proteins like IL-4 and IL-13 in these disorders which suggests potential therapeutic targets for treatment.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Carries out a dual function : signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.

See full target information Stat6 phospho Y641

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Publications (45)

Recent publications for all applications. Explore the full list and refine your search

Biomaterials research 29:0244 PubMed40873954

2025

Engineered Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Mitigate Liver Fibrosis by Delivering USP10 to Reprogram Macrophage Phenotype.

Applications

Unspecified application

Species

Unspecified reactive species

Siyuan Tian,Xia Zhou,Linhua Zheng,Jingyi Liu,Miao Zhang,Shuoyi Ma,Xiaohong Zheng,Guanya Guo,Ruobing Ju,Fangfang Yang,Yansheng Liu,Bo Li,Yinan Hu,Erzhuo Xia,Rui Su,Keshuai Sun,Lina Cui,Changcun Guo,Xinmin Zhou,Jingbo Wang,Yulong Shang,Ying Han

Scientific reports 15:30765 PubMed40841464

2025

Inflammatory cytokine interleukin-18 prevents murine miscarriage by inducing appropriate inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Yumi Horii,Hajime Ino,Fumiyuki Sasaki,Mariko Ishibashi,Eri Koike,Yoko Kawamoto,Richard A Flavell,Ryuji Ohashi,Shunji Suzuki,Yasuyuki Negishi,Rimpei Morita

Frontiers in pharmacology 16:1591394 PubMed40538548

2025

Aqueous extracts of L. alleviate atopic dermatitis by restoring skin barrier function.

Applications

Unspecified application

Species

Unspecified reactive species

Haobin Wei,Zhang Chen,Wenjie Lai,Wenxian Wang,Xiqing Bian,Limin Zhang,Xinzhi Li

CNS neuroscience & therapeutics 31:e70404 PubMed40277259

2025

Balancing Anti-Inflammation and Neurorepair: The Role of Mineralocorticoid Receptor in Regulating Microglial Phenotype Switching After Traumatic Brain Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Bin Zhang,Miao Bai,Mengshi Yang,Yumei Wang,Xueling Zhang,Xiyu Chen,Min Gao,Baiyun Liu,Guangzhi Shi

Cell death & disease 16:278 PubMed40216763

2025

Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages.

Applications

Unspecified application

Species

Unspecified reactive species

Chengju Luo,Chenqi Huang,Yuqi Zhu,Yuxin Zhou,Yansheng Qiao,Chenxiao Shi,Yuan Gao,Yongjian Guo,Libin Wei

European journal of medical research 30:22 PubMed39794821

2025

Efficacy of caerulomycin A in modulating macrophage polarization and cytokine response in a murine model of lipopolysaccharide-induced sepsis.

Applications

Unspecified application

Species

Unspecified reactive species

Jun Zhang,Shiyue Tang

Molecular medicine (Cambridge, Mass.) 30:220 PubMed39563244

2024

BMSC-derived exosomes promote osteoporosis alleviation via M2 macrophage polarization.

Applications

Unspecified application

Species

Unspecified reactive species

Yanbin Zhang,Jing Bai,Bin Xiao,Chunyan Li

PeerJ 12:e18507 PubMed39559329

2024

Cirsilineol improves anesthesia/surgery-induced postoperative cognitive dysfunction through attenuating oxidative stress and modulating microglia M1/M2 polarization.

Applications

Unspecified application

Species

Unspecified reactive species

Junli Du,Chao Chen,Jie Chen

PeerJ 12:e18324 PubMed39525474

2024

MiR-301b-3p promotes breast cancer development through inhibiting the expression of transforming growth factor-beta receptor 2.

Applications

Unspecified application

Species

Unspecified reactive species

Jian Lou,Xueni Liu,Yanru Xie,Minhua Wu,Weibo Mao,Xiaozhen Ying

Bioactive materials 39:302-316 PubMed38827174

2024

Netrin-1 co-cross-linked hydrogel accelerates diabetic wound healing in situ by modulating macrophage heterogeneity and promoting angiogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Futing Shu,Hongchao Huang,Shichu Xiao,Zhaofan Xia,Yongjun Zheng

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-STAT6 (phospho Y641) antibody [EPR22599-78]

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Immunoprecipitation - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Flow Cytometry (Intracellular) - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Immunoprecipitation - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Dot Blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

Western blot - Anti-STAT6 (phospho Y641) antibody [EPR22599-78] (AB263947)

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Primary Antibodies

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