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AB84873

Anti-STK38L/Ndr2 antibody [3563C2a]

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(2 Publications)

Mouse Monoclonal STK38L/Ndr2 antibody. Suitable for WB and reacts with Recombinant full length protein - Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human STK38L.

View Alternative Names

KIAA0965, NDR2, STK38L, Serine/threonine-protein kinase 38-like, NDR2 protein kinase, Nuclear Dbf2-related kinase 2

1 Images
Western blot - Anti-STK38L/Ndr2 antibody [3563C2a] (AB84873)
  • WB

Unknown

Western blot - Anti-STK38L/Ndr2 antibody [3563C2a] (AB84873)

Note : actual band size differs from predicted one, because the WB is depicting the recombinant fragment used as immunogen.

All lanes:

Western blot - Anti-STK38L/Ndr2 antibody [3563C2a] (ab84873)

All lanes:

immunising recombinant protein

Predicted band size: 54 kDa

Observed band size: 54 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

3563C2a

Isotype

IgG1

Carrier free

No

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human STK38L. The exact immunogen used to generate this antibody is proprietary information.

Q9Y2H1

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Alternative Products

Primary Antibodies

AB126106

Anti-STK38L/Ndr2 antibody

Western blot - Anti-STK38L/Ndr2 antibody (AB126106)

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Primary Antibodies

AB235304

Anti-STK38L/Ndr2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)

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Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Proteins & Peptides

AB125530

Recombinant human STK38L/Ndr2 protein

Functional Studies - Recombinant human STK38L/Ndr2 protein (AB125530)

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Cell Lines & Lysates

AB259162

Human STK38L (Ndr2) knockout HeLa cell lysate

Sanger Sequencing - Human STK38L (Ndr2) knockout HeLa cell lysate (AB259162)

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  • 0
Cell Lines & Lysates

AB265381

Human STK38L (Ndr2) knockout HeLa cell line

Sanger Sequencing - Human STK38L (Ndr2) knockout HeLa cell line (AB265381)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum.Filtered through a 0.22 µm membrane.
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 1% BSA, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.03% Tripotassium orthophosphate, 0.0225% Potassium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

STK38L also known as Ndr2 is a member of the serine/threonine kinase family and shares similarities with other Ndr family members. This protein plays a significant mechanical role in several cellular processes including regulation of cell growth and cell division. STK38L has a molecular mass of approximately 54 kDa. Researchers have observed its expression in various human tissues such as liver kidney and heart indicating its widespread functional roles in the body.
Biological function summary

STK38L acts as an important regulator by coordinating cell cycle-related activities and influences apoptosis. It is known to participate as part of the larger signaling complex interacting with scaffold proteins to ensure proper cell function. The protein mediates these biological processes through phosphorylation impacting various signaling networks and helping cells respond to different physiological conditions effectively.

Pathways

STK38L integrates into key signaling pathways such as the Hippo pathway which is essential for controlling organ size through the regulation of cell proliferation and apoptosis. This pathway involves other proteins like MST1/2 and LATS1/2 which closely interact with STK38L to maintain cellular homeostasis. The interaction with these proteins illustrates STK38L's critical positioning in cellular communication networks affecting the pathway’s outcome on cellular behavior.

STK38L is associated with certain cancers and neurodegenerative disorders. Aberrant function or regulation of STK38L may contribute to the development of conditions such as hepatocellular carcinoma and Alzheimer's disease. BRCA1 and Tau proteins are related to these diseases where STK38L’s interaction with or regulation of these proteins can influence disease progression providing potential therapeutic targets for intervention.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the regulation of structural processes in differentiating and mature neuronal cells.
See full target information STK38L
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Journal of gastroenterology and hepatology 33:1407-1412 PubMed29278438

2018

Role of heat shock factor 1 expression in the microenvironment of intrahepatic cholangiocarcinomas.

Applications

Unspecified application

Species

Unspecified reactive species

Yoichiro Kawashita,Yuji Morine,Yu Saito,Chie Takasu,Tetsuya Ikemoto,Shuichi Iwahashi,Hiroki Teraoku,Masato Yoshikawa,Satoru Imura,Toshiyuki Yagi,Mitsuo Shimada

Cell death & disease 2:e146 PubMed21490678

2011

SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds.

Applications

WB

Species

Unspecified reactive species

H H Cheung,M St Jean,S T Beug,R Lejmi-Mrad,E LaCasse,S D Baird,D F Stojdl,R A Screaton,R G Korneluk
View all publications
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Product promise

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