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AB169600

Anti-Stra6 antibody

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(1 Publication)

Mouse Polyclonal STRA6 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human STRA6.

View Alternative Names

PP14296, UNQ3126/PRO10282/PRO19578, STRA6, Receptor for retinol uptake STRA6, Retinol-binding protein receptor STRA6, Stimulated by retinoic acid gene 6 protein homolog

1 Images
Western blot - Anti-Stra6 antibody (AB169600)
  • WB

Unknown

Western blot - Anti-Stra6 antibody (AB169600)

All lanes:

Western blot - Anti-Stra6 antibody (ab169600) at 1 µg/mL

Lane 1:

Stra6 transfected 293T cell lysate at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Predicted band size: 74 kDa

true

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human STRA6.

Q9BX79

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Functions as a retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1 (PubMed : 18316031, PubMed : 22665496, PubMed : 9452451). Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (PubMed : 18316031, PubMed : 22665496). Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed : 21368206, PubMed : 22665496). Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid (PubMed : 18316031). STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (Probable). Does not transport retinoic acid (PubMed : 18316031).
See full target information STRA6
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Human molecular genetics : PubMed30986821

2019

The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel Berner,Ursula Hoja,Matthias Zenkel,James Julian Ross,Steffen Uebe,Daniela Paoli,Paolo Frezzotti,Robyn M Rautenbach,Ari Ziskind,Susan E Williams,Trevor R Carmichael,Michele Ramsay,Fotis Topouzis,Anthi Chatzikyriakidou,Alexandros Lambropoulos,Periasamy Sundaresan,Humaira Ayub,Farah Akhtar,Raheel Qamar,Juan C Zenteno,Marisa Cruz-Aguilar,Yury S Astakhov,Michael Dubina,Janey Wiggs,Mineo Ozaki,Friedrich E Kruse,Tin Aung,André Reis,Chiea Chuen Khor,Francesca Pasutto,Ursula Schlötzer-Schrehardt
View all publications
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Product promise

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