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AB77616

Anti-Stra6 antibody

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(2 Publications)

Goat Polyclonal STRA6 antibody. Suitable for WB and reacts with Rat samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Rat Stra6 aa 650 to C-terminus.

View Alternative Names

Receptor for retinol uptake STRA6, Retinol-binding protein receptor STRA6, Stimulated by retinoic acid gene 6 protein homolog

1 Images
Western blot - Anti-Stra6 antibody (AB77616)
  • WB

Supplier Data

Western blot - Anti-Stra6 antibody (AB77616)

Primary incubation 1 hour at room temperature. Detected by chemiluminescence.

All lanes:

Western blot - Anti-Stra6 antibody (ab77616) at 1 µg/mL

Lane 1:

Rat testes tissue lysate at 35 µg

Lane 2:

Rat testes tissue lysate at 35 µg with Immunizing peptide

Predicted band size: 74 kDa

Observed band size: 80-90 kDa

false

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat

Applications

WB

applications

Immunogen

Synthetic Peptide within Rat Stra6 aa 650 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q4QR83

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p>A 1 hour primary incubation is recommended for this product. Please note a non-specific band of ~80kDa.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: 0.5% BSA, 0.5% Tris buffered saline
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Functions as a retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid. STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency. Does not transport retinoic acid.
See full target information Stra6
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Poultry science 102:103028 PubMed37660449

2023

Adiponectin inhibits GnRH secretion via activating AMPK and PI3K signaling pathways in chicken hypothalamic neuron cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xing Wu,Yiqing Tao,Yangguang Ren,Zihao Zhang,Yudian Zhao,Yixiang Tian,Yijie Li,Meng Hou,Yulong Guo,Yujie Gong,Yanhua Zhang,Donghua Li,Hong Li,Ruirui Jiang,Guoxi Li,Xiaojun Liu,Xiangtao Kang,Yadong Tian

Diabetes 70:449-463 PubMed33199363

2020

Retinol-Binding Protein 4 Activates STRA6, Provoking Pancreatic β-Cell Dysfunction in Type 2 Diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Rong Huang,Xinxiu Bai,Xueyan Li,Xiaohui Wang,Lina Zhao
View all publications
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