Anti-Streptomycin antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Streptomycin plays a role in inhibiting bacterial protein synthesis making it effective against a variety of bacterial infections. It is not part of a larger complex but requires the presence of ATP for uptake by bacteria. Once inside streptomycin binds to the ribosomal subunit altering the codon-anticodon recognition site. This binding action interrupts normal bacterial functions and helps in the eradication of infections. Its spectrum of activity includes both gram-positive and gram-negative bacteria though it is more potent against aerobic bacteria.

Pathways

The mechanism of streptomycin intersects with the bacterial translational machinery pathways targeting ribosomal pathways leading to protein synthesis inhibition. It shares a connection with other aminoglycosides like gentamicin and kanamycin which also disrupt protein synthesis at the ribosome level. The disruption of these pathways halts bacterial growth therefore streptomycin and related drugs are utilized in various antibiotic treatments.