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AB5317

Anti-Sumo 3 antibody

2

(1 Review)

|

(4 Publications)

Rabbit Polyclonal SUMO3 antibody. Suitable for WB and reacts with Arabidopsis thaliana samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Arabidopsis thaliana SUMO3.

View Alternative Names

SUM3, At5g55170, MCO15.12, SUMO3, Small ubiquitin-related modifier 3, AtSUMO3

1 Images
Western blot - Anti-Sumo 3 antibody (AB5317)
  • WB

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Western blot - Anti-Sumo 3 antibody (AB5317)

Western blots of SUMO1 and SUMO3 antibody on arabidopsis extracts heat treated for the indicated times by moving them from 24 to 37 degrees C. The panel on the left was using ab5316, the panel on the right was using ab5317 - both antibodies were used at a dilution of 1/1000.

Western blots of SUMO1 and SUMO3 antibody on arabidopsis extracts heat treated for the indicated times by moving them from 24 to 37 degrees C. The panel on the left was using ab5316, the panel on the right was using ab5317 - both antibodies were used at a dilution of 1/1000.

Lane 1:

Western blot - Anti-Sumo 3 antibody (ab5317)

Lane 1:

Western blot - Anti-Sumo 1 antibody (<a href='/en-us/products/primary-antibodies/sumo-1-antibody-ab5316'>ab5316</a>)

Predicted band size: 11 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Arabidopsis thaliana

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Arabidopsis thaliana SUMO3.

Q9FLP5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Arabidopsis thaliana": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purity
Whole antiserum
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Sumo 3 also referred to as Small Ubiquitin-like Modifier 3 is a protein with a mass of approximately 11 kDa. It belongs to the SUMO family which modifies other proteins by attaching to them through a process called SUMOylation. Sumo 3 gets expressed widely in many tissues including the brain heart and skeletal muscles. It plays an important role in cellular processes such as nuclear-cytosolic transport transcriptional regulation and DNA repair.
Biological function summary

Sumo 3 functions in post-translational modification of proteins and often forms part of protein complexes. This modification can alter the protein's localization stability and activity. Sumo 3 activity influences cell cycle progression mitosis and stress response. SUMOylation including Sumo 3 adjusts protein interactions and functions impacting cellular homeostasis and modulation of transcription factors.

Pathways

Sumo 3 participates in the DNA repair and cellular stress response pathways. Through these pathways Sumo 3 closely interacts with proteins such as P53 an important protein in cell cycle regulation and apoptosis. Sumo 3 aids in facilitating DNA damage repair and protecting cells from apoptosis under stress helping maintain genomic integrity.

Sumo 3 involvement has a relation to cancer and neurodegenerative disease. Alterations in SUMOylation patterns involving Sumo 3 can lead to cancer development due to ineffective DNA repair and apoptosis. Furthermore in neurodegenerative disease Sumo 3 modulates protein aggregation processes increasing or reducing accumulation of neurotoxic proteins. Sumo 3 often interacts with proteins like huntingtin in Huntington's disease influencing disease progression through modulation of protein aggregation.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Ubiquitin-like protein which can be covalently attached to target lysines as a monomer (By similarity). Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process (By similarity). Promotes NPR1 sumoylation to activate defense gene expression and regulate its degradation (PubMed : 26269953).
See full target information SUMO3
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

The Plant cell 35:1532-1547 PubMed36705512

2023

SMC5/6 complex-mediated SUMOylation stimulates DNA-protein cross-link repair in Arabidopsis.

Applications

Unspecified application

Species

Unspecified reactive species

Eva Dvořák Tomaštíková,Klara Prochazkova,Fen Yang,Jitka Jemelkova,Andreas Finke,Annika Dorn,Mahmoud Said,Holger Puchta,Ales Pecinka

The Plant cell 29:508-525 PubMed28223439

2017

Sumoylation of RNA Polymerase Promotes Viral Infection by Counteracting the Host NPR1-Mediated Immune Response.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaofei Cheng,Ruyi Xiong,Yinzi Li,Fangfang Li,Xueping Zhou,Aiming Wang

Plant physiology 149:1529-40 PubMed19151129

2009

Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation.

Applications

WB

Species

Arabidopsis thaliana

Ruchika Budhiraja,Rebecca Hermkes,Stefan Müller,Jürgen Schmidt,Thomas Colby,Kishore Panigrahi,George Coupland,Andreas Bachmair

The Journal of biological chemistry 278:6862-72 PubMed12482876

2002

The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.

Applications

Unspecified application

Species

Unspecified reactive species

Jasmina Kurepa,Joseph M Walker,Jan Smalle,Mark M Gosink,Seth J Davis,Tessa L Durham,Dong-Yul Sung,Richard D Vierstra
View all publications
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