JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB13498

Anti-Superoxide Dismutase 1 antibody

5

(23 Reviews)

|

(232 Publications)

Anti-Superoxide Dismutase 1 antibody (ab13498) is a rabbit polyclonal antibody for Western Blot, IP, IHC-P, IHC-Fr, ICC/IF, ELISA. Suitable for Coral, Cow, Dog, Drosophila, Fish, Hamster, Human, Mollusk, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus.

- Over 190 publications
- Trusted since 2004

View Alternative Names

Superoxide dismutase [Cu-Zn], Hydrogen sulfide oxidase, Superoxide dismutase 1, hSod1, SOD1

2 Images
Western blot - Anti-Superoxide Dismutase 1 antibody (AB13498)
  • WB

Supplier Data

Western blot - Anti-Superoxide Dismutase 1 antibody (AB13498)

Block : 1.5% BSA.

All lanes:

Western blot - Anti-Superoxide Dismutase 1 antibody (ab13498) at 0.2 µg/mL

All lanes:

HeLa (Human epithelial cell line from cervix adenocarcinoma) lysate at 15 µg

Secondary

All lanes:

Donkey Anti-Rabbit IgG HRP 1 hr at RT

Predicted band size: 15 kDa

Observed band size: 23 kDa

false

Western blot - Anti-Superoxide Dismutase 1 antibody (AB13498)
  • WB

CiteAb

Western blot - Anti-Superoxide Dismutase 1 antibody (AB13498)

Western Blotting using Anti-Superoxide Dismutase 1 antibody, ab13498. Publication image from Liu, Y. et al., 2018, Nat Commun, 30356100. Legend direct from paper.

HPV16 E7-induced LDHA nuclear translocation implicates in cervical cancer development. a, b, c LDHANLS increases tumor growth in xenograft nude mice model. Representative images (mouse NO. 1 with Vec on the left flank and WT on the right flank, and mouse NO. 1′ with NLS on the left flank and NES on the right flank) of HeLa LDHA KO with Vec/WT/NLS/NES putback xenograft mice (a). Dissected tumors in xenograft mice transplanted with HeLa LDHA KO with Vec/WT/NLS/NES putback cells (b) and the tumor volumes on day 30 were represented (c). d LDHANLS tumor shows an elevated H3K79me2, NRF2, SOD1, and MYC levels. The level of H3K79me2 and the expression of NRF2, SOD1, and MYC in two pairs of representative tumors were analyzed by western blotting. β-actin and histone H3 were used as loading control. e LDHA nuclear translocation are positively correlated with H3K79 trimethylation in K14-HPV16 transgenic mice. Representative IHC images of HPV16 E7 expression, LDHA localization, and H3K79me3 level at indicated time point in TALEN-mediated targeting E7 of K14-HPV16 transgenic mice. n = 3 per group. Scale bar, 50 µm. f HPV16 E7 levels, LDHA nuclear translocation and H3K79 trimethylation are positively correlated with each other in human cervical tumor tissues. The 52 cases were divided into four groups on the basis of their tumor HPV16 E7 expression scores. Horizontal lines represent the median. Data are shown as mean ± SEM. The p values were determined by two-tailed t-test. The values of p < 0.05 were considered statistically significant. *, **, and *** denote p < 0.05, p < 0.01, and p < 0.001, respectively. NS means non significant. g Proposed molecular mechanism model of a noncanonical role for LDHA in responds to HR-HPV infection. PYR, pyruvate, LAC, lactate,α-KB,α-ketobutyrate, andα-HB,α-hydroxybutyrate

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, Monkey, Xenopus laevis, Cow, Fish, Coral, Pig, African green monkey, Sheep, Mouse, Hamster, Drosophila melanogaster, Mollusk, Rabbit, Dog, Rat

Applications

ICC/IF, WB, ELISA, IHC-Fr, IHC-P, IP

applications

Immunogen

Synthetic Peptide within Human SOD1. The exact immunogen used to generate this antibody is proprietary information.

P00441

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "African green monkey": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCFr-species-checked": "predicted", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Coral": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Cow": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Dog": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Drosophila melanogaster": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Fish": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Hamster": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Mollusk": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Monkey": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Pig": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Rabbit": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Sheep": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Vervet monkey": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Xenopus laevis": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Shinder et al 2001.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>See Downs et al 2002.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>See Abreview.</p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }

Product details

What is this antibody validated in?
Anti-Superoxide Dismutase 1 antibody (ab13498) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in African green monkey, Coral, Cow, Dog, Drosophila melanogaster, Fish, Hamster, Human, Mollusk, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis samples.

What is the molecular weight of Superoxide Dismutase 1?
Anti-Superoxide Dismutase 1 (ab13498) specifically detects a band for Superoxide Dismutase 1 (UniProt: P00441) at a molecular weight of 16kDa.

Trusted by the scientific community
Anti-Superoxide Dismutase 1 (ab13498) was first used in a scientific publication in 2004 and has been cited over 190 times in peer-reviewed journals.

Reviewed by scientists
Anti-Superoxide Dismutase 1 (ab13498) has over 20 independent reviews from customers.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
This antibody was purified on an antigen coupled sepharose column.
Storage buffer
pH: 7 Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Superoxide Dismutase 1 (SOD1) also known as Cu/Zn SOD or simply dismutase is an enzyme important for the detoxification of superoxide radicals. SOD1 catalyzes the conversion of two superoxide molecules into oxygen and hydrogen peroxide maintaining cellular redox balance. This enzyme typically exhibits a mass of approximately 32 kDa. SOD1 is expressed in the cytoplasm of cells throughout the body including tissues like liver kidney and brain.
Biological function summary

The enzyme functions as a homodimer with each subunit containing a copper and zinc ion. These metal ions are essential for the catalytic activity of SOD1 as the copper ion participates in electron transfer while the zinc ion provides structural stability. The enzyme protects cells from oxidative stress by neutralizing excess reactive oxygen species ensuring cellular health and functioning.

Pathways

SOD1 plays an important role in the cellular antioxidant defense system and is a part of the reactive oxygen species (ROS) metabolic pathway. It works in conjunction with catalase and glutathione peroxidase to limit oxidative damage within cells. The close interaction between these enzymes highlights the interdependence within the antioxidant defense network emphasizing their role in maintaining cellular homeostasis.

Mutations in the SOD1 gene are linked to familial Amyotrophic Lateral Sclerosis (ALS) a neurodegenerative condition. In ALS aberrant SOD1 proteins may lead to increased oxidative stress and motor neuron damage. Research also connects SOD1 to the pathogenesis of Alzheimer's disease where oxidative stress is a contributing factor. These associations underline SOD1's significance in neurodegenerative diseases highlighting potential therapeutic targets for interventions focused on oxidative stress management.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Destroys radicals which are normally produced within the cells and which are toxic to biological systems (PubMed : 24140062). Catalyzes the oxidation of hydrogen sulfide (H2S) to sulfate, playing an important role in detoxifying H2S and limiting the accumulation of reactive sulfur species (RSS) such as persulfides and polysulfides (PubMed : 36630448).
See full target information SOD1

Publications (232)

Recent publications for all applications. Explore the full list and refine your search

Cell biology and toxicology 41:129 PubMed40897829

2025

Celastrol modulates IRS1 expression to alleviate ovarian aging and to enhance follicular development.

Applications

Unspecified application

Species

Unspecified reactive species

Yao Jiang,Yonghua Shi,Meng Lv,Tao Wang,Penghao Wang,Xiaolong Yuan,Fei Gao,Bin Ma

Comprehensive Physiology 15:e70031 PubMed40765038

2025

Different Fasting Methods Combined With Running Exercise Regulate Glucose Metabolism via AMPK/SIRT1/BDNF Pathway in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Xukai Wang,Jian Shi,Yinhuan Li,Lizi Zhou,Linjing Xu,Junming Wang,Chunhong Liu,Boji Liang

Alzheimer's & dementia : the journal of the Alzheimer's Association 21:e70117 PubMed40189792

2025

Platelets mirror changes in the frontal lobe antioxidant system in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Huriye Ercan,Christina Maria Reumiller,Jacqueline Mühlberger,Felicia Hsu,Georg Johannes Schmidt,Ellen Umlauf,Ingrid Miller,Eduard Rappold,Johannes Attems,Rudolf Oehler,Maria Zellner

PloS one 20:e0313803 PubMed40173155

2025

PM2.5 from automobile exhaust induces apoptosis in male rat germ cells via the ROS-UPRmt signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Cao Wang,Yingchi Zhao,Bin Liu,Zhen Luo,Guangxu Zhou,Kaiyi Mao

Investigative ophthalmology & visual science 66:60 PubMed39992672

2025

Untargeted Tear Proteomics in a Large South-Asian Cohort Reveals Inflammatory Signaling, ECM Remodeling, and Altered Metabolism in Keratoconus.

Applications

Unspecified application

Species

Unspecified reactive species

Ramaraj Kannan,Rohit Shetty,Trailokyanath Panigrahi,Siew Kwan Koh,Pooja Khamar,Vrushali Deshpande,Rudy M M A Nuijts,Marlies Gijs,Krishnatej Nishtala,Lei Zhou,Arkasubhra Ghosh

The journal of headache and pain 25:207 PubMed39587478

2024

Intrathecal lactate dehydrogenase A inhibitors FX11 and oxamate alleviate chronic constriction injury-induced nociceptive sensitization through neuroinflammation and angiogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Hao-Jung Cheng,Nan-Fu Chen,Wu-Fu Chen,Zong-Sheng Wu,Yu-Yo Sun,Wei-Nung Teng,Fu-Wei Su,Chun-Sung Sung,Zhi-Hong Wen

International journal of molecular sciences 25: PubMed39408720

2024

Rutin Ameliorates ALS Pathology by Reducing SOD1 Aggregation and Neuroinflammation in an SOD1-G93A Mouse Model.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyu Du,Quanxiu Dong,Jie Zhu,Lingjie Li,Xiaolin Yu,Ruitian Liu

Pharmaceuticals (Basel, Switzerland) 17: PubMed39338355

2024

Novel Therapeutic Effects of L. Methanol Extracts in Macular Degeneration Caused by Blue Light in A2E-Laden ARPE-19 Cells and Retina of BALB/c Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Ayun Seol,Ji-Eun Kim,You-Jeong Jin,Hee-Jin Song,Yu-Jeong Roh,Tae-Ryeol Kim,Eun-Seo Park,Ki-Ho Park,So-Hae Park,Muhammad Salah Uddin,Sang-Woo Lee,Young-Woo Choi,Dae-Youn Hwang

Acta neuropathologica communications 12:144 PubMed39227882

2024

ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Pavol Zelina,Anna Aster de Ruiter,Christy Kolsteeg,Ilona van Ginneken,Harmjan R Vos,Laura F Supiot,Boudewijn M T Burgering,Frank J Meye,Jan H Veldink,Leonard H van den Berg,R Jeroen Pasterkamp

Journal of virology 98:e0126224 PubMed39194237

2024

Protective role of cytosolic prion protein against virus infection in prion-infected cells.

Applications

Unspecified application

Species

Unspecified reactive species

Hideyuki Hara,Junji Chida,Batzaya Batchuluun,Etsuhisa Takahashi,Hiroshi Kido,Suehiro Sakaguchi
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com