Rabbit Polyclonal SUSD2 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SUSD2 aa 500-700.
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- Journal of personalized medicine 11:2021Characterization of the Endometrial MSC Marker Ectonucleoside Triphosphate Diphosphohydrolase-2 (NTPDase2/CD39L1) in Low- and High-Grade Endometrial Carcinomas: Loss of Stromal Expression in the Invasive Phenotypes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAitor Rodríguez-Martínez,Carla Trapero,August Vidal,Josep Maria Piulats,Inmaculada Gómez de Aranda,Jean Sévigny,Maria Eulàlia Fernández-Montolí,Jordi Ponce,Xavier Matias-Guiu,Mireia Martín-SatuéPubMed 33922226
- International journal of molecular sciences 20:2019Impaired Expression of Ectonucleotidases in Ectopic and Eutopic Endometrial Tissue Is in Favor of ATP Accumulation in the Tissue Microenvironment in Endometriosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCarla Trapero et. al.PubMed 31698766
- Purinergic signalling 15:225-2362019The ectonucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in human endometrium: a novel marker of basal stroma and mesenchymal stem cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCarla Trapero et. al.PubMed 31123897
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human SUSD2 aa 500-700. The exact immunogen used to generate this antibody is proprietary information. Database link Q9UGT4
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/1000.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
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Target data
Function
May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994).
Alternative names
Sushi domain-containing protein 2, SUSD2
Recommended products
Rabbit Polyclonal SUSD2 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SUSD2 aa 500-700.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human SUSD2 aa 500-700. The exact immunogen used to generate this antibody is proprietary information. Database link Q9UGT4
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
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Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
SUSD2 also known as Sushi Domain Containing 2 is a protein involved in cellular activities such as cell adhesion and signaling. The protein has a molecular mass of approximately 80 kDa. SUSD2 expresses in various tissues including the brain lungs and reproductive organs. It often localizes at the cell membrane where it participates in interactions with other cellular components.
- Biological function summary
This protein contributes to cellular communication and immune regulation. SUSD2 is a part of complexes that help mediate cell-to-cell interactions. These complexes play roles in the immune response influencing how the body responds to different stimuli. SUSD2 modulates activities such as phagocytosis and cell migration which are important in maintaining a healthy immune system.
- Pathways
SUSD2 is involved in immune-related and cellular signaling pathways. It interacts with proteins like integrins and collagens which are involved in the extracellular matrix organization pathway. SUSD2 also participates in pathways related to immune regulation working together with proteins such as TNF-alpha and interleukins. This involvement is important for coordinating cellular responses necessary for immune defense.
- Associated diseases and disorders
SUSD2 possesses links to cancer and autoimmune diseases. Research indicates its possible involvement in certain cancer types like breast cancer where it might interact with oncogenes and tumor suppressors. SUSD2 also shows associations with autoimmune diseases possibly due to its role in immune system regulation. In cases such as rheumatoid arthritis it may interact with inflammatory cytokines contributing to disease pathology.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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3 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SUSD2 antibody (ab121214)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling SUSD2 with ab121214 at 1/500 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SUSD2 antibody (ab121214)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human duodenum tissue labelling SUSD2 with ab121214 at 1/500 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SUSD2 antibody (ab121214)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver tissue labelling SUSD2 with ab121214 at 1/500 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.
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