AB182147

Anti-SUSD2 antibody [EPR8913(2)]

RabMAb
Recombinant
What is this?

Be the first to review this product! Submit a review

(2 Publications)

Rabbit Recombinant Monoclonal SUSD2 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

View Alternative Names

Sushi domain-containing protein 2, SUSD2

1 Images

Supplier Data

Western blot - Anti-SUSD2 antibody [EPR8913(2)] (AB182147)

All lanes:

Western blot - Anti-SUSD2 antibody [EPR8913(2)] (ab182147) at 1/20000 dilution

All lanes:

SK-BR-3 lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 90 kDa

false

Carrier free

Anti-SUSD2 antibody [EPR8913(2)] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR8913(2)

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" } } }

style

left-column

Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 Preservative: 0.01% Sodium azide Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SUSD2 also known as Sushi Domain Containing 2 is a protein involved in cellular activities such as cell adhesion and signaling. The protein has a molecular mass of approximately 80 kDa. SUSD2 expresses in various tissues including the brain lungs and reproductive organs. It often localizes at the cell membrane where it participates in interactions with other cellular components.

Biological function summary

This protein contributes to cellular communication and immune regulation. SUSD2 is a part of complexes that help mediate cell-to-cell interactions. These complexes play roles in the immune response influencing how the body responds to different stimuli. SUSD2 modulates activities such as phagocytosis and cell migration which are important in maintaining a healthy immune system.

Pathways

SUSD2 is involved in immune-related and cellular signaling pathways. It interacts with proteins like integrins and collagens which are involved in the extracellular matrix organization pathway. SUSD2 also participates in pathways related to immune regulation working together with proteins such as TNF-alpha and interleukins. This involvement is important for coordinating cellular responses necessary for immune defense.

SUSD2 possesses links to cancer and autoimmune diseases. Research indicates its possible involvement in certain cancer types like breast cancer where it might interact with oncogenes and tumor suppressors. SUSD2 also shows associations with autoimmune diseases possibly due to its role in immune system regulation. In cases such as rheumatoid arthritis it may interact with inflammatory cytokines contributing to disease pathology.

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed : 25351403). May play a role in breast tumorigenesis (PubMed : 23131994).

See full target information SUSD2

style

left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine reports 23: PubMed33537815

2021

Circ‑TOP2A acts as a ceRNA for miR‑346 and contributes to glioma progression via the modulation of sushi domain‑containing 2.

Applications

Unspecified application

Species

Unspecified reactive species

Junzhi Sang,Xing Li,Luting Lv,Chunyu Zhang,Xiaoqian Zhang,Guoan Li

Oncotarget 11:2290-2301 PubMed32595828

2020

expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model.

Applications

Unspecified application

Species

Unspecified reactive species

Jordan N Sheets,Mitch E Patrick,Kristi A Egland

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SUSD2 antibody [EPR8913(2)]

Western blot - Anti-SUSD2 antibody [EPR8913(2)] (AB182147)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (2)

Alternative Products

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Product promise