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AB229222

Anti-Syntenin 2 antibody

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(1 Publication)

Rabbit Polyclonal Syntenin 2 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human SDCBP2.

View Alternative Names

SITAC18, SDCBP2, Syntenin-2, Similar to TACIP18, Syndecan-binding protein 2, SITAC

1 Images
Western blot - Anti-Syntenin 2 antibody (AB229222)
  • WB

Supplier Data

Western blot - Anti-Syntenin 2 antibody (AB229222)

12% SDS-PAGE gel.

All lanes:

Western blot - Anti-Syntenin 2 antibody (ab229222) at 1/1000 dilution

All lanes:

U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell lysate at 30 µg

Predicted band size: 32 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human SDCBP2. The exact immunogen used to generate this antibody is proprietary information.

Q9H190

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Complementary Products

Primary Antibodies

AB19903

Anti-Syntenin antibody

KO Validated

Western blot - Anti-Syntenin antibody (AB19903)

  • 4
  • 4
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Proteins & Peptides

AB101950

Recombinant Human Syntenin protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human Syntenin protein (His tag N-Terminus) (AB101950)

  • 0
  • 0
Primary Antibodies

AB133497

Anti-Flotillin 1 antibody [EPR6041]

RabMAb|Recombinant|KO Validated|20ul selling size

Flow Cytometry (Intracellular) - Anti-Flotillin 1 antibody [EPR6041] (AB133497)

  • 5
  • 6
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Syntenin 2 also known as tacstd2 is a multifunctional protein with a molecular mass of approximately 32 kDa. It is an adaptor protein that facilitates various intracellular processes through its PDZ domains. Syntenin 2 establishes interactions with other proteins by binding to their C-terminal sequences. This protein is expressed in numerous human tissues including the lung liver and kidneys highlighting its widespread function across the body.
Biological function summary

Syntenin 2 impacts cell signaling membrane trafficking and cytoskeletal organization. It functions within complexes that play roles in vital cellular communication processes. Syntenin 2 can interact with other proteins such as syndecans and various transmembrane proteins enabling pathways that regulate cell movement and communication. These interactions suggest its involvement in intracellular transport and signal transduction.

Pathways

The role of Syntenin 2 centers on the regulation of the Wnt signaling and the VEGF pathway. It participates by anchoring signaling components in specific locations in the cell influencing cellular responses. Its association with proteins like axin in the Wnt pathway and VEGF receptors in the VEGF pathway shows its versatility in coordinating complex signal networks that affect cell proliferation survival and migration.

Syntenin 2 has shown associations with cancer and fibrosis. In cancers dysregulation of pathways involving Syntenin 2 such as the Wnt signaling can contribute to abnormal cell growth and metastasis. In fibrosis its interaction with fibronectin and integrins might initiate excessive extracellular matrix production leading to tissue scarring. Understanding Syntenin 2's interaction with these proteins could provide insights into therapeutic approaches for related diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed : 15961997).
See full target information SDCBP2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 14:52 PubMed36681682

2023

Wdr4 promotes cerebellar development and locomotion through Arhgap17-mediated Rac1 activation.

Applications

Unspecified application

Species

Unspecified reactive species

Pei-Rung Wu,Shang-Yin Chiang,Robert Midence,Wen-Chao Kao,Chun-Lun Lai,I-Cheng Cheng,Shen-Ju Chou,Chih-Cheng Chen,Chih-Yang Huang,Ruey-Hwa Chen
View all publications
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Product promise

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