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Rabbit Polyclonal SYT11 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SYT11.

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Images

Western blot - Anti-SYT11 antibody (AB110766), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Synthetic Peptide within Human SYT11. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BT88

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested
Mouse
Predicted
Rat
Predicted

Tested
Tested

Species
Human
Dilution info
1/500.00000 - 1/1000.00000
Notes

-

Predicted
Predicted

Species
Mouse, Rat
Dilution info
-
Notes

-

Target data

Function

Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+). Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval. Plays an important role in dopamine transmission by regulating endocytosis and the vesicle-recycling process. Essential component of a neuronal vesicular trafficking pathway that differs from the synaptic vesicle trafficking pathway but is crucial for development and synaptic plasticity. In macrophages and microglia, inhibits the conventional cytokine secretion, of at least IL6 and TNF, and phagocytosis. In astrocytes, regulates lysosome exocytosis, mechanism required for the repair of injured astrocyte cell membrane (By similarity). Required for the ATP13A2-mediated regulation of the autophagy-lysosome pathway (PubMed:27278822).

Alternative names

KIAA0080, SYT11, Synaptotagmin-11, Synaptotagmin XI, SytXI

Recommended products

Rabbit Polyclonal SYT11 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SYT11.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Synthetic Peptide within Human SYT11. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BT88
Purification technique
Affinity purification Immunogen
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
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1 product image

  • Western blot - Anti-SYT11 antibody (ab110766), expandable thumbnail

    Western blot - Anti-SYT11 antibody (ab110766)

    All lanes: Western blot - Anti-SYT11 antibody (ab110766) at 1/500 dilution

    Lane 1: Extracts from COLO205 cells at 30 µg

    Lane 2: Extracts from COLO205 cells at 30 µg with immunising peptide

    Predicted band size: 48 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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