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AB326667

Anti-TAOK2 (phospho S181) + TAOK1 (phospho S181) + TAOK3 (phospho S177) antibody [SR1151]

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Rabbit Recombinant Monoclonal TAOK1 phospho S181 antibody. Suitable for WB, IHC-P and reacts with Human samples.

View Alternative Names

KIAA1361, MAP3K16, MARKK, TAOK1, Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, MARK Kinase, Prostate-derived sterile 20-like kinase 2, Thousand and one amino acid protein kinase 1, hKFC-B, PSK-2, PSK2, Prostate-derived STE20-like kinase 2, hTAOK1

1 Images
Western blot - Anti-TAOK2 (phospho S181) + TAOK1 (phospho S181) + TAOK3 (phospho S177) antibody [SR1151] (AB326667)
  • WB

Supplier Data

Western blot - Anti-TAOK2 (phospho S181) + TAOK1 (phospho S181) + TAOK3 (phospho S177) antibody [SR1151] (AB326667)

All lanes : Primary antibody at 1/1000 dilution

Lane 1 : 293 cell lysate
Lane 2 : 293 treated with Lambda phosphatase for 30min cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) at 1/20000 dilution
Predicted band size : 116 kDa
Observed band size : 110-140 kDa

Exposure time : 11 seconds

All lanes:

Western blot - Anti-TAOK2 (phospho S181) + TAOK1 (phospho S181) + TAOK3 (phospho S177) antibody [SR1151] (ab326667) at 1/1000 dilution

Lane 1:

293 cell lysate at 20 µg

Lane 2:

293 treated with Lambda phosphatase for 30min cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG H&L (HRP) at 1/20000 dilution

Predicted band size: 116 kDa

Observed band size: 110-140 kDa

false

Exposure time: 11s

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

SR1151

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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Product details

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis : regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade. Plays an essential role in the regulation of neuronal development in the central nervous system (PubMed : 33565190). Also plays a role in the regulation of neuronal migration to the cortical plate (By similarity).
See full target information TAOK1 pS181
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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