AB818

Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade

Name: Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade (ab818) | Abcam
Brand: Abcam Limited
SKU: AB818
Price: 400 USD
Availability: InStock
Rating: 4 (39 reviews)

Lab Essentials
What is this?

(39 Reviews)

(285 Publications)

Anti-TATA binding protein TBP antibody [1TBP18] - ChIP Grade (ab818) is a mouse monoclonal antibody detecting TATA binding protein TBP in Western Blot, Flow Cytometry, IP, IHC-P, IHC-Fr, ICC/IF, ELISA, EM, ChIP. Suitable for Human, Mouse, Rat.

- Over 260 publications
- Trusted since 2002

View Alternative Names

GTF2D1, TF2D, TFIID, TBP, TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit

2 Images

ChIP

Lab

ChIP - Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade (AB818)

Chromatin was prepared from U2OS cells according to the Abcam X-ChIP protocol. Cells were fixed with formaldehyde for 10 min. The ChIP was performed with 25 μg of chromatin, 8 μg of ab818 (blue), and 20 μl of Protein A/G sepharose beads. No antibody was added to the beads control (yellow). The last wash was performed with final wash buffer containing 250 mM NaCl. The immunoprecipitated DNA was quantified by real time PCR (Taqman and sybr green approach). Primers and probes are located in the core promoter region of the genes.

This image was generated using the ascites version of the product.

Flow Cyt

Lab

Flow Cytometry - Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade (AB818)

Overlay histogram showing HeLa cells stained with ab818 (red line). The cells were fixed with 100% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab818, 1μg/1x10⁶ cells) for 30 min at 22°C. The secondary antibody used was Goat Anti-Mouse IgG H&L (DyLight^® 488) preadsorbed (ab96879) secondary antibody at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was Mouse IgG1 [ICIGG1] (ab91353, 2μg/1x10⁶ cells) used under the same conditions. Acquisition of >5,000 events was performed.

This image was generated using the ascites version of the product.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

1TBP18

Isotype

IgG1

Carrier free

Reacts with

Human, Mouse, Rat

Applications

WB, IHC-P, ELISA, ICC/IF, ChIP, IP, EMSA, ICC, Flow Cyt, IHC-Fr, ChIP/Chip

applications

Immunogen

Synthetic Peptide within Human TBP. The exact immunogen used to generate this antibody is proprietary information.

P20226

Epitope

Within amino acid residues 1-20 of human, mouse and rat TBP.The specific epitope for this antibody is accessible when the C-terminal domain of TBP is removed or when TBP is complexed with DNA.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ChIP" : {"fullname" : "ChIP", "shortname":"ChIP"}, "ChIPChip" : {"fullname" : "ChIP on chip", "shortname":"ChIP/Chip"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "EMSA" : {"fullname" : "Electrophoretic Mobility Shift Assay", "shortname":"EMSA"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ChIP-species-checked": "testedAndGuaranteed", "ChIP-species-dilution-info": "5-10 µg for 25 µg chromatin", "ChIP-species-notes": "", "ChIPChip-species-checked": "guaranteed", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-6 µg for 10^6 Cells", "FlowCyt-species-notes": "<a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> and <a href='/en-us/products/primary-antibodies/mouse-igg1-ct6-isotype-control-ab81216'>ab81216</a> - Mouse monoclonal IgG1, are suitable for use as an isotype control with this antibody.We recommend Goat Anti-Mouse IgG H&L (DyLight® 488) preadsorbed (<a href='/en-us/products/secondary-antibodies/goat-mouse-igg-h-l-dylight-488-preadsorbed-ab96879'>ab96879</a>) secondary antibody", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "guaranteed", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Mouse": { "ChIP-species-checked": "predicted", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "ChIPChip-species-checked": "guaranteed", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "guaranteed", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Rat": { "ChIP-species-checked": "predicted", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "ChIPChip-species-checked": "guaranteed", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "guaranteed", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Drosophila melanogaster": { "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "ChIPChip-species-checked": "notRecommended", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "notRecommended", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "1-6 µg for 10^6 Cells", "FlowCyt-species-notes": "<a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> and <a href='/en-us/products/primary-antibodies/mouse-igg1-ct6-isotype-control-ab81216'>ab81216</a> - Mouse monoclonal IgG1, are suitable for use as an isotype control with this antibody.We recommend Goat Anti-Mouse IgG H&L (DyLight® 488) preadsorbed (<a href='/en-us/products/secondary-antibodies/goat-mouse-igg-h-l-dylight-488-preadsorbed-ab96879'>ab96879</a>) secondary antibody", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "notRecommended", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "notRecommended", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Saccharomyces cerevisiae": { "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "ChIPChip-species-checked": "notRecommended", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "notRecommended", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "notRecommended", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "notRecommended", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Silk worm": { "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "ChIPChip-species-checked": "notRecommended", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "notRecommended", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "notRecommended", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "notRecommended", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Xenopus laevis": { "ChIP-species-checked": "notRecommended", "ChIP-species-dilution-info": "", "ChIP-species-notes": "", "ChIPChip-species-checked": "notRecommended", "ChIPChip-species-dilution-info": "", "ChIPChip-species-notes": "", "ICC-species-checked": "notRecommended", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "1-6 µg for 10^6 Cells", "FlowCyt-species-notes": "<a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> and <a href='/en-us/products/primary-antibodies/mouse-igg1-ct6-isotype-control-ab81216'>ab81216</a> - Mouse monoclonal IgG1, are suitable for use as an isotype control with this antibody.We recommend Goat Anti-Mouse IgG H&L (DyLight® 488) preadsorbed (<a href='/en-us/products/secondary-antibodies/goat-mouse-igg-h-l-dylight-488-preadsorbed-ab96879'>ab96879</a>) secondary antibody", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "We recommend Rabbit Anti-Mouse IgG H&;L (Alkaline Phosphatase) (<a href='/en-us/products/secondary-antibodies/rabbit-mouse-igg-h-l-alkaline-phosphatase-ab6729'>ab6729</a>) secondary antibody.", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "EMSA-species-checked": "notRecommended", "EMSA-species-dilution-info": "", "EMSA-species-notes": "", "IHCFr-species-checked": "notRecommended", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" } } }

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Product details

What is this antibody validated in?
Anti-TATA binding protein TBP antibody [1TBP18] - ChIP Grade (ab818) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA, Electron microscopy (EM), ChIP in Human, Mouse, Rat samples.

What is the molecular weight of TATA binding protein TBP?
Anti-TATA binding protein TBP [1TBP18] - ChIP Grade (ab818) specifically detects a band for TATA binding protein TBP (UniProt: P20226) at a molecular weight of 38kDa.

Trusted by the scientific community
Anti-TATA binding protein TBP [1TBP18] - ChIP Grade (ab818) was first used in a scientific publication in 2002 and has been cited over 260 times in peer-reviewed journals.

Reviewed by scientists
Anti-TATA binding protein TBP [1TBP18] - ChIP Grade (ab818) has over 35 independent reviews from customers.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

Purified from TCS

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The TATA binding protein (TBP) also known as TBP or TFIID (Transcription Factor IID) is a central player in transcription initiation. This protein weighing approximately 38 kDa binds to the TATA box a DNA sequence found in the promoter region of many genes especially those transcribed by RNA polymerase II. TBP facilitates the loading of the transcription machinery onto DNA enabling the start of transcription. It is found inside the nucleus of eukaryotic cells present across diverse cell types owing to its role in gene expression.

Biological function summary

TBP serves as a pivotal anchor in the assembly of the transcription preinitiation complex contributing to the process by bending DNA to assist other transcription factors such as TFIIA and TFIIB in binding. Its role in this complex illustrates its importance in regulating gene expression at a fundamental level. TBP’s interaction with other transcription factors ensures precise transcription regulation reflecting its significant contribution to cellular activities.

Pathways

TBP acts within the RNA polymerase II transcription initiation pathway and is integral in regulating gene expression. TBP's involvement is critical for the process of starting the transcription of mRNA. In its pathway TBP interacts with proteins like TFIID helping to anchor other transcription factors in the complex. By collaborating with these proteins TBP shapes gene regulatory networks essential for a wide range of cellular functions.

TBP is linked to conditions such as spinocerebellar ataxia type 17 (SCA17) and Huntington's disease. SCA17 is associated with mutations in the TBP gene that disrupt its usual functioning leading to neurodegeneration. In Huntington's disease TBP's interaction with proteins such as huntingtin may influence nuclear signaling pathways involved in disease progression. The understanding of TBP’s role in these disorders underlines its relevance in research focused on genetic diseases and transcription-related pathologies.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed : 33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed : 2194289, PubMed : 2363050, PubMed : 2374612, PubMed : 27193682, PubMed : 33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed : 27007846, PubMed : 33795473). The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (PubMed : 33795473). TBP forms the TFIID-A module together with TAF3 and TAF5 (PubMed : 33795473). TBP is a general transcription factor that functions at the core of the TFIID complex (PubMed : 2194289, PubMed : 2363050, PubMed : 2374612, PubMed : 27193682, PubMed : 33795473, PubMed : 9836642). During assembly of the core PIC on the promoter, as part of TFIID, TBP binds to and also bends promoter DNA, irrespective of whether the promoter contains a TATA box (PubMed : 33795473). Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed : 26638071). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC during RNA polymerase I-dependent transcription (PubMed : 15970593). The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter (PubMed : 15970593). SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA (PubMed : 15970593).

See full target information TBP

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Publications (285)

Recent publications for all applications. Explore the full list and refine your search

Genes & development 39:652-675 PubMed40240143

2025

Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate.

Applications

Unspecified application

Species

Unspecified reactive species

Reuben Franklin,Brian Zhang,Jonah Frazier,Meijuan Chen,Brian T Do,Sally Padayao,Kun Wu,Matthew G Vander Heiden,Christopher R Vakoc,Jae-Seok Roe,Maria Ninova,Jernej Murn,David B Sykes,Sihem Cheloufi

Cell 188:998-1018.e26 PubMed39826545

2025

Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Giuseppe Quarto,Andrea Li Greci,Martin Bizet,Audrey Penning,Irina Primac,Frédéric Murisier,Liliana Garcia-Martinez,Rodrigo L Borges,Qingzeng Gao,Pradeep K R Cingaram,Emilie Calonne,Bouchra Hassabi,Céline Hubert,Adèle Herpoel,Pascale Putmans,Frédérique Mies,Jérôme Martin,Louis Van der Linden,Gaurav Dube,Pankaj Kumar,Romuald Soin,Abhay Kumar,Anurag Misra,Jie Lan,Morgane Paque,Yogesh K Gupta,Arnaud Blomme,Pierre Close,Pierre-Olivier Estève,Elizabeth A Caine,Kristin M Riching,Cyril Gueydan,Danette L Daniels,Sriharsa Pradhan,Ramin Shiekhattar,Yael David,Lluis Morey,Jana Jeschke,Rachel Deplus,Evelyne Collignon,François Fuks

Biotechnology journal 19:e202400474 PubMed39655408

2024

Selective Recruitment of a Synthetic Histone Acetyltransferase Can Boost CHO Cell Productivity.

Applications

Unspecified application

Species

Unspecified reactive species

Sienna P Butterfield,Rebecca E Sizer,Fay L Saunders,Robert J White

Molecular systems biology 20:1346-1371 PubMed39548324

2024

Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting.

Applications

Unspecified application

Species

Unspecified reactive species

David Steinbrecht,Igor Minia,Miha Milek,Johannes Meisig,Nils Blüthgen,Markus Landthaler

Cancers 16: PubMed39272864

2024

Development of New Diffuse Large B Cell Lymphoma Mouse Models.

Applications

Unspecified application

Species

Unspecified reactive species

Syed Hassan Mehdi,Ying-Zhi Xu,Leonard D Shultz,Eunkyung Kim,Yong Gu Lee,Samantha Kendrick,Donghoon Yoon

Cells 13: PubMed39120286

2024

N-SREBP2 Provides a Mechanism for Dynamic Control of Cellular Cholesterol Homeostasis.

Applications

Unspecified application

Species

Unspecified reactive species

Tozen Ozkan-Nikitaras,Dominika J Grzesik,Lisa E L Romano,J P Chapple,Peter J King,Carol C Shoulders

Gaceta medica de Mexico 160:1-8 PubMed38753562

2024

Drosophila in the study of hTBP protein interactions in the development and modeling of SCA17.

Applications

Unspecified application

Species

Unspecified reactive species

Rubén J Montalvo-Méndez,Marcela Cárdenas-Tueme,Diana Reséndez-Pérez

The Journal of biological chemistry 300:107146 PubMed38460939

2024

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression.

Applications

Unspecified application

Species

Unspecified reactive species

Karina L Bursch,Christopher J Goetz,Guanming Jiao,Raymundo Nuñez,Michael D Olp,Alisha Dhiman,Mallika Khurana,Michael T Zimmermann,Raul A Urrutia,Emily C Dykhuizen,Brian C Smith

Heliyon 10:e23167 PubMed38169774

2024

Inhibition of TAF1B impairs ribosome biosynthesis and suppresses cell proliferation in stomach adenocarcinoma through promoting c-MYC mRNA degradation.

Applications

Unspecified application

Species

Unspecified reactive species

Hang-Fei Chen,Zhang-Ping Li,Qi Wu,Chun Yu,Jing-Yi Yan,Yong-Feng Bai,Sheng-Mei Zhu,Mao-Xiang Qian,Ming Liu,Li-Feng Xu,Zheng Peng,Feng Zhang

Pharmaceutics 15: PubMed38140111

2023

IDF-11774 Induces Cell Cycle Arrest and Apoptosis by Inhibiting HIF-1α in Gastric Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Won-Ho Kim,Min-Jee Kim,Jun-O Jin,Peter C W Lee

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade

ChIP - Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade (AB818)

Flow Cytometry - Anti-TATA binding protein TBP antibody [1TBP18] - Loading Control and ChIP Grade (AB818)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Epitope

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (285)

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