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Rabbit Recombinant Monoclonal TEAD4 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human TEAD4.

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Images

Western blot - Anti-TEF1/TEAD-1 + TEAD4 + TEA domain family member 2/ETF + TEAD3 Antibody [S09-9D9] (AB317403), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7.4
Preservative: 0.01% Sodium azide
Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Fragment Protein within Human TEAD4. Database link Q15561

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested

Tested
Tested

Species
Human
Dilution info
1/1000
Notes

-

Target data

Function

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

Additional Targets

TEAD1, TEAD2, TEAD3

Alternative names

RTEF1, TCF13L1, TEF3, TEAD4, Transcriptional enhancer factor TEF-3, TEA domain family member 4, Transcription factor 13-like 1, Transcription factor RTEF-1, TEAD-4

Recommended products

Rabbit Recombinant Monoclonal TEAD4 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human TEAD4.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Fragment Protein within Human TEAD4. Database link Q15561
Clone number
S09-9D9
Purification technique
Affinity purification
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Western blot - Anti-TEF1/TEAD-1 + TEAD4 + TEA domain family member 2/ETF + TEAD3 Antibody [S09-9D9] (ab317403), expandable thumbnail

    Western blot - Anti-TEF1/TEAD-1 + TEAD4 + TEA domain family member 2/ETF + TEAD3 Antibody [S09-9D9] (ab317403)

    Predicted bands:
    TEAD1 48 kDa
    TEAD2 49 kDa
    TEAD3 49 kDa
    TEAD4 48 kDa

    All lanes: Western blot - Anti-TEF1/TEAD-1 + TEAD4 + TEA domain family member 2/ETF + TEAD3 Antibody [S09-9D9] (ab317403) at 1/1000 dilution

    Lane 1: K562 cell lysate

    Lane 2: HeLa cell lysate

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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