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AB122722

Anti-TELO2 antibody

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(3 Publications)

Rabbit Polyclonal TELO2 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TELO2 aa 350-500.

View Alternative Names

KIAA0683, TELO2, Telomere length regulation protein TEL2 homolog, Protein clk-2 homolog, hCLK2

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-TELO2 antibody (AB122722)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-TELO2 antibody (AB122722)

ab122722, at 4 ug/ml, staining TELO2 in Human cell line U-251 MG by Immunoflourosence.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TELO2 antibody (AB122722)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TELO2 antibody (AB122722)

ab122722, at 1/50 dilution, staining TELO2 in paraffin-embedded Human urinary bladder tissue by Immunohistochemistry.

Western blot - Anti-TELO2 antibody (AB122722)
  • WB

Unknown

Western blot - Anti-TELO2 antibody (AB122722)

All lanes:

Western blot - Anti-TELO2 antibody (ab122722) at 1/250 dilution

Lane 1:

RT-4

Lane 2:

U-251 MG

Lane 3:

Human plasma

Lane 4:

Human liver lysate

Lane 5:

Human tonsil lysate

Predicted band size: 92 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human TELO2 aa 350-500. The exact immunogen used to generate this antibody is proprietary information.

Q9Y4R8

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
See full target information TELO2
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Cell death discovery 7:164 PubMed34226511

2021

The proteolytic landscape of cells exposed to non-lethal stresses is shaped by executioner caspases.

Applications

Unspecified application

Species

Unspecified reactive species

María Del Carmen Conde-Rubio,Roman Mylonas,Christian Widmann

Oncology reports 45:523-534 PubMed33416177

2021

TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2.

Applications

Unspecified application

Species

Unspecified reactive species

Zheng Guo,Xiufang Zhang,Huabin Zhu,Nanying Zhong,Xiaoning Luo,Yu Zhang,Fuping Tu,Jinghua Zhong,Xiangcai Wang,Jue He,Li Huang

Oncotarget 7:46056-46066 PubMed27329594

2016

Overexpression of TELO2 decreases survival in human high-grade gliomas.

Applications

WB, IHC

Species

Unspecified reactive species, Unspecified reactive species

Shao-Wei Feng,Ying Chen,Wen-Chiuan Tsai,Hsin-Ying Clair Chiou,Sheng-Tang Wu,Li-Chun Huang,Chin Lin,Chih-Chuan Hsieh,Yun-Ju Yang,Dueng-Yuan Hueng
View all publications
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Product promise

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