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AB228614

Anti-TFB2M antibody

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(1 Publication)

Rabbit Polyclonal TFB2M antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human TFB2M.

View Alternative Names

NS5ATP5, TFB2M, Hepatitis C virus NS5A-transactivated protein 5, Mitochondrial 12S rRNA dimethylase 2, Mitochondrial transcription factor B2, HCV NS5A-transactivated protein 5, h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2

1 Images
Western blot - Anti-TFB2M antibody (AB228614)
  • WB

Supplier Data

Western blot - Anti-TFB2M antibody (AB228614)

12% SDS-PAGE gel.

All lanes:

Western blot - Anti-TFB2M antibody (ab228614) at 1/500 dilution

Lane 1:

Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate

Lane 2:

TFB2M transfected HEK-293T whole cell lysate

Predicted band size: 45 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human TFB2M. The exact immunogen used to generate this antibody is proprietary information.

Q9H5Q4

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA (PubMed : 12068295, PubMed : 15526033, PubMed : 20410300, PubMed : 29149603). In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand (PubMed : 15526033, PubMed : 29149603). Stimulates transcription independently of the methyltransferase activity (PubMed : 12897151).
See full target information TFB2M
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Neurology(R) neuroimmunology & neuroinflammation 10: PubMed37591767

2023

Electrolyte Imbalance in Anti-LGI1 Encephalitis: It Is Not All in Your Head.

Applications

Unspecified application

Species

Unspecified reactive species

Avi Gadoth,Michal Nisnboym,Yifat Alcalay,Asia Zubkov,Idit Schwartz,Doron Schwartz,Marana Abboud,Tamar Rubinek,Ofer Yossepowitch,Talia Weinstein
View all publications
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Product promise

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