AB180619

Anti-TFPI antibody

Name: Anti-TFPI antibody (ab180619) | Abcam
Brand: Abcam Limited
SKU: AB180619
Price: 525 USD
Availability: InStock

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(5 Publications)

Rabbit Polyclonal TFPI antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human, Mouse samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TFPI aa 1-250.

View Alternative Names

LACI, TFPI1, TFPI, Tissue factor pathway inhibitor, Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, EPI

5 Images

Immunocytochemistry/ Immunofluorescence - Anti-TFPI antibody (AB180619)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-TFPI antibody (AB180619)

Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab180619. Blue DAPI for nuclear staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TFPI antibody (AB180619)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TFPI antibody (AB180619)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver cancer tissue labelling TFPI with ab180619 at 1/100. Magnification : 200x.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TFPI antibody (AB180619)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse kidney tissue labelling TFPI with ab180619 at 1/100. Magnification : 200x.

Unknown

Western blot - Anti-TFPI antibody (AB180619)

All lanes:

Western blot - Anti-TFPI antibody (ab180619) at 1/500 dilution

Lane 1:

293T cell lysate

Lane 2:

MCF-7 cell lysate

Lane 3:

Mouse lung tissue lysate

Lane 4:

Mouse heart tissue lysate

Lane 5:

Mouse spleen tissue lysate

Predicted band size: 35 kDa

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Supplier Data

Western blot - Anti-TFPI antibody (AB180619)

All lanes:

Western blot - Anti-TFPI antibody (ab180619) at 1/500 dilution

Lane 1:

HepG2 cell line extract

Lane 2:

HeLa cell line extract

Predicted band size: 35 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human TFPI aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

P10646

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<a href='/en-us/products/primary-antibodies/rabbit-igg-polyclonal-isotype-control-chip-grade-ab171870'>ab171870</a> - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<a href='/en-us/products/primary-antibodies/rabbit-igg-polyclonal-isotype-control-chip-grade-ab171870'>ab171870</a> - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

See full target information TFPI

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:3976 PubMed38729948

2024

TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia.

Applications

Unspecified application

Species

Unspecified reactive species

Jun-Kai Ma,Li-Da Su,Lin-Lin Feng,Jing-Lin Li,Li Pan,Qupei Danzeng,Yanwei Li,Tongyao Shang,Xiao-Lin Zhan,Si-Ying Chen,Shibo Ying,Jian-Rao Hu,Xue Qun Chen,Qi Zhang,Tingbo Liang,Xin-Jiang Lu

Frontiers in cell and developmental biology 12:1344070 PubMed38440076

2024

Lung lymphatic endothelial cells undergo inflammatory and prothrombotic changes in a model of chronic obstructive pulmonary disease.

Applications

Unspecified application

Species

Unspecified reactive species

Anjali Trivedi,Tyler M Lu,Barbara Summers,Kihwan Kim,Alexander J Rhee,Sean Houghton,Derek E Byers,Raphaël Lis,Hasina Outtz Reed

Cellular physiology and biochemistry : internation 43:1392-1401 PubMed29017171

2017

Role of the TGFβ/PDCD4/AP-1 Signaling Pathway in Nasopharyngeal Carcinoma and Its Relationship to Prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Ma,Shu-Hong Xuan,Yan Li,Zhi-Ping Zhang,Xin-Hua Li

Molecular vision 22:424-35 PubMed27168718

2016

Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy.

Applications

IHC, WB

Species

Unspecified reactive species, Unspecified reactive species

Ahmed M Abu El-Asrar,Mohammad Mairaj Siddiquei,Mohd Imtiaz Nawaz,Gert De Hertogh,Ghulam Mohammad,Kaiser Alam,Ahmed Mousa,Ghislain Opdenakker

Cellular physiology and biochemistry : internation 38:110-21 PubMed26742121

2016

Comparative Profiling of Triple-Negative Breast Carcinomas Tissue Glycoproteome by Sequential Purification of Glycoproteins and Stable Isotope Labeling.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang Chen,Jindao Wu,Huaxing Huang,Qiang Ding,Xiaoan Liu,Lin Chen,Xiaoming Zha,Mengdi Liang,Jing He,Qiannan Zhu,Shui Wang,Tiansong Xia

View all publications

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