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AB27001

Anti-TGE antibody

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(2 Publications)

Rabbit Polyclonal TGE antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human TGM3.

View Alternative Names

Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, Transglutaminase-3, TG(E), TGE, TGase E, TGase-3, TGM3

1 Images
Western blot - Anti-TGE antibody (AB27001)
  • WB

Unknown

Western blot - Anti-TGE antibody (AB27001)

20 µg of human epidermal lysate was loaded. Following protein transfer ab27001 was applied at a dilution of 1/500. An anti-Rabbit secondary antibody (non-Abcam) was used at 1/2000. Molecular weight 76 kDa.

All lanes:

Western blot - Anti-TGE antibody (ab27001)

Predicted band size: 76 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human TGM3. The exact immunogen used to generate this antibody is proprietary information.

Q08188

Specificity

This antibody is specific to TGE from epidermal cell.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purity
Whole antiserum
Storage buffer
Constituents: Whole serum
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
See full target information TGM3
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Oncology reports 43:864-876 PubMed32020212

2020

TGM3 functions as a tumor suppressor by repressing epithelial‑to‑mesenchymal transition and the PI3K/AKT signaling pathway in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yifei Feng,Dongjian Ji,Yuanjian Huang,Bing Ji,Yue Zhang,Jie Li,Wen Peng,Chuan Zhang,Dongsheng Zhang,Yueming Sun,Ziwei Xu

Journal of immunology (Baltimore, Md. : 1950) 186:4474-80 PubMed21335491

2011

Dermatitis herpetiformis sera or goat anti-transglutaminase-3 transferred to human skin-grafted mice mimics dermatitis herpetiformis immunopathology.

Applications

IHC-Fr

Species

Mouse

John J Zone,Linda A Schmidt,Ted B Taylor,Christopher M Hull,Michael C Sotiriou,Troy D Jaskowski,Harry R Hill,Laurence J Meyer
View all publications
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Product promise

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