AB166705

Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11]

Name: Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (ab166705) | Abcam
Brand: Abcam Limited
SKU: AB166705
Price: 545 USD
Availability: InStock

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(4 Publications)

Mouse Monoclonal TGF beta Receptor III/TGFBR3 antibody. Suitable for ELISA, WB and reacts with Recombinant fragment, Human, Mouse, Recombinant fragment - Human samples. Cited in 4 publications.

View Alternative Names

Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III, TGFBR3

3 Images

ELISA - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

ELISA

Unknown

ELISA - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

ELISA using ab166705 at 1/10000 dilution
Red : Control Antigen (100 ng)
Purple : Antigen (10 ng)
Green : Antigen (50 ng)
Blue : Antigen (100 ng)

Unknown

Western blot - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

All lanes:

Western blot - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (ab166705) at 1/500 dilution

Lane 1:

Jurkat cell lysate

Lane 2:

HeLa cell lysate

Lane 3:

MCF7 cell lysate

Lane 4:

F9 cell lysate

Lane 5:

SK N SH cell lysate

Lane 6:

NIH 3T3 cell lysate

Predicted band size: 93 kDa

false

Unknown

Western blot - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

Expected MW of recombinant protein is 44.1 kDa.

All lanes:

Western blot - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (ab166705) at 1/500 dilution

All lanes:

recombinant Human TGF beta Receptor III/TGFBR3 protein

Predicted band size: 101 kDa,28 kDa,38 kDa,42 kDa,45 kDa,59 kDa,92 kDa,93 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

1C5H11

Isotype

IgG1

Carrier free

Reacts with

Mouse, Human

Applications

WB, ELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "" }, "Mouse": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "" }, "Chimpanzee": { "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant fragment": { "ELISA-species-checked": "testedAndGuaranteed", "ELISA-species-dilution-info": "1/10000", "ELISA-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant fragment - Human": { "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "" } } }

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Product details

This product was changed from ascites to supernatant. Lot no's high than GR206347-9 are from Tissue Culture Supernatant.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

Preservative: 0.05% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cell surface receptor that regulates diverse cellular processes including cell proliferation, differentiation, migration, and apoptosis (PubMed : 12958365, PubMed : 19416857). Initiates BMP, inhibin, and TGF-beta signaling pathways by interacting with different ligands including TGFB1, BMP2, BMP5, BMP7 or GDF5 (PubMed : 18184661). Alternatively, acts as a cell surface coreceptor for BMP ligands, serving to enhance ligand binding by differentially regulating BMPR1A/ALK3 and BMPR1B/ALK6 receptor trafficking (PubMed : 19726563). Promotes epithelial cell adhesion, focal adhesion formation and integrin signaling during epithelial cell spreading on fibronectin (PubMed : 22562249). By interacting with the scaffolding protein beta-arrestin2/ARRB2, regulates migration or actin cytoskeleton and promotes the activation of CDC42 as well as the inhibition of NF-kappa-B (PubMed : 19416857, PubMed : 19325136). In gonadotrope cells, acts as an inhibin A coreceptor and regulates follicle-stimulating hormone (FSH) levels and female fertility (By similarity). Plays a role in the inhibition of directed and random cell migration in epithelial cells by altering the actin cytoskeletal organization (PubMed : 19416857). Participates in epithelial-mesenchymal transformation (EMT) upon binding to BMP2 or TGFB2, by activating the PAR6/SMURF1/RHOA pathway (By similarity).. (Microbial infection) May act as a receptor for human cytomegalovirus in different cell types by interacting with HCMV trimer composed of GO, GH and GL.

See full target information TGFBR3

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

BMC pulmonary medicine 22:371 PubMed36180862

2022

LncRNA H19 alleviates sepsis-induced acute lung injury by regulating the miR-107/TGFBR3 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiuling Hao,Huiqiang Wei

BioFactors (Oxford, England) 47:801-818 PubMed34129254

2021

Dihydroartemisinin alleviates hepatic fibrosis through inducing ferroptosis in hepatic stellate cells.

Applications

Unspecified application

Species

Unspecified reactive species

Zili Zhang,Xian Wang,Zilong Wang,Zhiyue Zhang,Yashi Cao,Zonghui Wei,Jiangjuan Shao,Anping Chen,Feng Zhang,Shizhong Zheng

Oncotarget 7:38398-38407 PubMed27223264

2016

H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction.

Applications

Unspecified application

Species

Unspecified reactive species

Lisa Zuckerwise,Jing Li,Lingeng Lu,Yi Men,Tingting Geng,Catalin S Buhimschi,Irina A Buhimschi,Radek Bukowski,Seth Guller,Michael Paidas,Yingqun Huang

Current eye research 41:1035-1043 PubMed26673553

2015

Transforming Growth Factor Beta 1 Modulates the Functional Expression of the Neurokinin-1 Receptor in Human Keratocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Sandrine Le Roux,Gabor Borbely,Marta Słoniecka,Ludvig J Backman,Patrik Danielson

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11]

ELISA - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

Western blot - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

Western blot - Anti-TGF beta Receptor III/TGFBR3 antibody [1C5H11] (AB166705)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Secondary Antibodies

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (4)

Product promise