Rabbit Polyclonal THAP11 antibody. Suitable for IHC-P, WB and reacts with Mouse, Human, Rat samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human THAP11 aa 1-300.
View Alternative Names
HRIHFB2206, THAP11, THAP domain-containing protein 11
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-THAP11 antibody (AB154942)
Immunohistochemical analysis of paraffin-embedded Hela xenograft, labeling THAP11 using ab154942 at 1/500.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-THAP11 antibody (AB154942)
Immunohistochemical analysis of paraffin-embedded RT2 xenograft, labeling THAP11 using ab154942 at 1/500.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-THAP11 antibody (AB154942)
Immunohistochemical analysis of paraffin-embedded C2C12 xenograft, labeling THAP11 using ab154942 at 1/500.
- WB
Unknown
Western blot - Anti-THAP11 antibody (AB154942)
10% SDS PAGE
All lanes:
Western blot - Anti-THAP11 antibody (ab154942) at 1/3000 dilution
All lanes:
NT2D1 whole cell lysate at 30 µg
Predicted band size: 34 kDa
false
Reactivity data
Properties and storage information
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Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
THAP11 plays a significant role in gene regulation and transcriptional control. It acts as part of a transcriptional repressor complex influencing cell proliferation and differentiation. THAP11 modulates the expression of genes that are important for maintaining cellular homeostasis and development. It interacts with other proteins and genetic elements to ensure proper cellular functioning. By controlling the expression of target genes THAP11 guides essential cellular processes impacting normal and pathological states.
Pathways
THAP11 is involved in multiple biological processes especially those related to stem cell maintenance and embryonic development. It is actively engaged in pathways like the Wnt signaling pathway where it regulates genes important for cell growth and division. THAP11 also interacts with proteins such as beta-catenin and TCF7L2 within these pathways modulating their activities to direct cell fate decisions. Its functional integration into these pathways highlights the importance of THAP11 in regulating developmental and cellular diversification processes.
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Target data
Publications (2)
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Journal of biochemical and molecular toxicology 38:e23705 PubMed38602237
2024
Applications
Unspecified application
Species
Unspecified reactive species
Journal of gastrointestinal oncology 12:1704-1717 PubMed34532121
2021
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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