AB203022

Anti-Thy1.1 antibody

Name: Anti-Thy1.1 antibody (ab203022) | Abcam
Brand: Abcam Limited
SKU: AB203022
Rating: 1 (3 reviews)

(3 Reviews)

(1 Publication)

Rabbit Polyclonal CD90 / Thy1 antibody. Suitable for IHC-P, Flow Cyt and reacts with Rat, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Rat Thy1 aa 1-100 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

CD90, Thy-1, Thy1, Thy-1 membrane glycoprotein, Thy-1 antigen

2 Images

Flow Cytometry - Anti-Thy1.1 antibody (AB203022)

Flow Cyt

Unknown

Flow Cytometry - Anti-Thy1.1 antibody (AB203022)

Flow Cytometry of Mouse Kidney with ab217798 at 1/50

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thy1.1 antibody (AB203022)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thy1.1 antibody (AB203022)

Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded rat brain tissue labeling Thy1.1 using ab203022 at a 1/200 dilution. DAB staining, followed by conjugation to the secondary antibody and DAB staining.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat

Applications

IHC-P, Flow Cyt

applications

Immunogen

Synthetic Peptide within Rat Thy1 aa 1-100 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

P01830

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" }, "Mouse": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/50", "FlowCyt-species-notes": "<p></p>" }, "Rat": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" }, "Sheep": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Thy1.1 also known as CD90 is a cell surface glycoprotein with a mass of approximately 25-35 kDa. This protein is expressed on a variety of cells including T cells stem cells neurons and fibroblasts. Thy1.1 is important in cell-cell and cell-matrix interactions playing a role in cell adhesion and signaling. It is an important marker used to identify different cell populations especially in murine models. Researchers often study Thy1.1 for its role in immunology and neuroscience due to its widespread expression across different tissues.

Biological function summary

The functions of Thy1.1 involve cell communication and signal transduction. Thy1.1 does not form a known complex but interacts with other molecules to influence the cellular environment. It is involved in processes such as apoptosis inflammation and fibrosis. The protein facilitates cell activation and differentiation by interacting with integrins and other surface molecules further affecting cellular responses.

Pathways

Thy1.1 substantially participates in signaling pathways such as the T-cell receptor (TCR) signaling pathway and fibrosis-related pathways. In the TCR signaling pathway Thy1.1 modulates T cell activation and proliferation. Within fibrosis Thy1.1 involvement affects extracellular matrix regulation and fibrosis progression. It associates with proteins such as integrins and fibronectin which are important in these pathways contributing to diverse cellular outcomes.

Thy1.1 shows connections to conditions like fibrosis and multiple sclerosis. In fibrosis Thy1.1 plays a role in the regulation of extracellular matrix deposition affecting tissue remodeling and repair. It interacts with proteins involved in fibrosis signaling such as transforming growth factor-beta (TGF-β). In the context of multiple sclerosis Thy1.1 expression impacts immune cell functions potentially influencing disease progression. Researchers study these associations to explore therapeutic strategies targeting Thy1.1-related pathways.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information Thy1

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 10:102 PubMed30718480

2019

Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2.

Applications

Unspecified application

Species

Unspecified reactive species

Vasanthy Vigneswara,Zubair Ahmed

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Thy1.1 antibody

Flow Cytometry - Anti-Thy1.1 antibody (AB203022)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thy1.1 antibody (AB203022)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Alternative Products

Primary Antibodies

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Secondary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Product promise