Anti-TLR9 antibody
5
(1 Review)
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(28 Publications)
Rabbit Polyclonal TLR9 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse samples. Cited in 28 publications. Immunogen corresponding to Synthetic Peptide within Human TLR9.
View Alternative Names
CD289, UNQ5798/PRO19605, TLR9, Toll-like receptor 9
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TLR9 antibody (AB37154)
ab37154 at 2 µg/ml staining TLR9 in mouse spleen cells by IHC.
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-TLR9 antibody (AB37154)
Immunofluorescence of TLR9 in Mouse Spleen cells using ab37154 at 10 ug/ml.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TLR9 antibody (AB37154)
Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse spleen tissue labeling TLR9 with Anti-TLR9 antibody (ab37154) at 5μg/ml.
- WB
Supplier Data
Western blot - Anti-TLR9 antibody (AB37154)
Lane 1:
Western blot - Anti-TLR9 antibody (ab37154) at 0.5 µg/mL
Lane 2:
Western blot - Anti-TLR9 antibody (ab37154) at 1 µg/mL
All lanes:
Mouse spleen cell lysate
Predicted band size: 115 kDa
false
- WB
CiteAb
Western blot - Anti-TLR9 antibody (AB37154)
TLR9 western blot using anti-TLR9 antibody ab37154. Publication image and figure legend from Hua, F., Wang, J., et al., 2011, J Neuroinflammation, PubMed 21549006.
ab37154 was used in this publication in western blot. This may not be the same as the application(s) guaranteed by Abcam. For a full list of applications guaranteed by Abcam for ab37154 please see the product overview.
Expression of TLR2, TLR9, Ccl-2 and Cxcl-10 in traumatically injured brain with or without progesterone treatment. The figures show that TLR2, Ccl-2 and Cxcl-10, but not TLR9, significantly increased in traumatically injured brain compared with sham controls. Administration of PROG inhibited the increase of Ccl-2 and Cxcl-10, but increased the expression of TLR9 in sham and injured brain. Representative images of western blots are shown on the top of A and B. Note : a : compared with sham; b : compared with TBI; d : compared with TBI : p < 0.05. Sham : n = 3; Sham+P : n = 3; TBI : n = 5; TBI+P : n = 5.
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Reactivity data
Properties and storage information
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Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
TLR9 recognizes and binds to microbial DNA triggering an immune response. It is part of the Toll-like receptor family which plays an important role in the innate immune system. TLR9 engages in the formation of complexes with other molecules such as MyD88 an adaptor protein to propagate downstream signaling. This leads to the activation of transcription factors that stimulate cytokine production promoting inflammation and defense against infections.
Pathways
TLR9 participates significantly in the NF-kB activation pathway and the type I interferon signaling cascade. During these processes TLR9 interacts with proteins like IRAK4 and TRAF6. In the NF-kB pathway TLR9's role in the early immune response is coordinated with other Toll-like receptors to detect pathogen-related patterns and initiate adaptive immunity. Its influence on type I interferon signaling facilitates antiviral defense mechanisms.
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Target data
Publications (28)
Recent publications for all applications. Explore the full list and refine your search
Biomolecules 15: PubMed40867523
2025
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Cancers 16: PubMed39123407
2024
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Scientific reports 14:15789 PubMed38982195
2024
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Journal of microbiology and biotechnology 33:1213-1227 PubMed37416999
2023
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EMBO reports 24:e54006 PubMed36416244
2022
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Frontiers in molecular neuroscience 15:1008203 PubMed36277489
2022
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Physiological research 71:259-273 PubMed35275698
2022
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Asian journal of andrology 24:380-385 PubMed34643549
2021
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Cancers 13: PubMed34203465
2021
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Biochemical pharmacology 188:114559 PubMed33872571
2021
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Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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