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AB122562

Anti-Tm9sf3 antibody

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(1 Publication)

Rabbit Polyclonal Tm9sf3 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TM9SF3 aa 50-150.

View Alternative Names

SMBP, UNQ245/PRO282, TM9SF3, Transmembrane 9 superfamily member 3, EP70-P-iso, SM-11044-binding protein

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-Tm9sf3 antibody (AB122562)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Tm9sf3 antibody (AB122562)

Immunofluorescent staining of Human cell line U-2 OS shows positivity in vesicles. Recommended concentration of ab122562 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tm9sf3 antibody (AB122562)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tm9sf3 antibody (AB122562)

ab122562, at 1/50 dilution, staining Tm9sf3 in Paraffin Embedded Human duodenum tissue by Immunohistochemistry.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human TM9SF3 aa 50-150. The exact immunogen used to generate this antibody is proprietary information.

Q9HD45

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle|Store undiluted
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Tm9sf3 protein also known as Tumor Protein Transmembrane 9 Superfamily Member 3 is a transmembrane protein with a mass of approximately 77 kDa. It primarily locates within the membrane compartments of cells and is expressed in various tissues including prostate tissue and several other organs. Although detailed expression profiles in specific tissues such as marmosets require further investigation current data highlights its relevance in cellular processes.
Biological function summary

Tm9sf3 plays a significant role in vesicular trafficking and membrane organization. This protein contributes to critical biological processes by facilitating transport and communication between cellular compartments. Tm9sf3 often functions as a part of a larger protein complex interacting dynamically with other membrane-associated proteins to execute these roles efficiently.

Pathways

The protein engages notably in intracellular signaling processes. Tm9sf3 is involved in the regulation of the endocytic and exocytic pathways where it cooperates closely with well-known proteins such as Rab GTPases. These GTPases act as molecular switches that mediate vesicle movement and fusion within cells establishing a functional link that Tm9sf3 supports within these pathways.

Tm9sf3 has been implicated in cancerous transformations and immune system dysregulations. Specifically studies suggest a connection between Tm9sf3 and various forms of cancer including those affecting prostate tissue. Through these conditions Tm9sf3 interacts with other proteins like tumor suppression genes and immune regulators that influence the development and progression of these diseases. Understanding its precise role in such contexts is ongoing but could offer insights into potential therapeutic targets.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information TM9SF3
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10:e2206792 PubMed36775874

2023

EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1.

Applications

Unspecified application

Species

Unspecified reactive species

Yihui Pan,Guannan Shu,Liangmin Fu,Kangbo Huang,Xinwei Zhou,Chengpeng Gui,Huashan Liu,Xiaohan Jin,Minyu Chen,Pengju Li,Junjie Cen,Zihao Feng,Jun Lu,Zhenhua Chen,Jiaying Li,Quanhui Xu,Yinghan Wang,Hui Liang,Zhu Wang,Qiong Deng,Wei Chen,Junhang Luo,Jiefeng Yang,Jiaxing Zhang,Jinhuan Wei
View all publications
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