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AB126094

Anti-TMED7 antibody

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(2 Publications)

Rabbit Polyclonal TMED7 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TMED7 aa 1-200.

View Alternative Names

CGI-109, TMED7, Transmembrane emp24 domain-containing protein 7, p24 family protein gamma-3, p27, p24gamma3

1 Images
Western blot - Anti-TMED7 antibody (AB126094)
  • WB

Unknown

Western blot - Anti-TMED7 antibody (AB126094)

Gel concentration : 12%

All lanes:

Western blot - Anti-TMED7 antibody (ab126094) at 1/1000 dilution

Lane 1:

293T whole cell lysate at 30 µg

Lane 2:

A431 whole cell lysate at 30 µg

Predicted band size: 25 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human TMED7 aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

Q9Y3B3

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Zebrafish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMED7 also known as Transmembrane emp24 domain-containing protein 7 is a member of the p24 protein family involved in the vesicular trafficking process. It has a molecular mass of approximately 24 kDa. TMED7 is typically expressed in the endoplasmic reticulum and Golgi apparatus. It has an important role in maintaining the structure and function of these organelles by helping facilitate the transport of proteins between these two cellular compartments.
Biological function summary

TMED7 is a component of the coat protein complex I (COPI) vesicular transport mechanism. It participates in retrograde transport which is essential for recycling Golgi-resident enzymes back to the endoplasmic reticulum. This protein acts by recognizing specific cargo molecules that need to be transported associating with the COPI complex to move these loads in the retrograde direction.

Pathways

The TMED7 protein is actively involved in the secretory pathway and protein trafficking. It plays a part in the Golgi to endoplasmic reticulum transport alongside proteins like TMED9 that also associate with COPI vesicles. This involvement is important for ensuring a balanced protein distribution and proper cellular function influencing processes such as protein folding and modification.

TMED7 connects to conditions impacting the trafficking machinery like congenital disorders of glycosylation. Aberrations in TMED7 and related proteins such as TMED10 can disrupt the normal intracellular transport pathway leading to protein mislocalization and functional deficiencies. It also has implications in immune system disorders as changes in its pathway can affect the secretion of cytokines which play a role in inflammatory responses.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications.
See full target information TMED7
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Oncogenesis 14:34 PubMed40885723

2025

Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse.

Applications

Unspecified application

Species

Unspecified reactive species

Lucile Bansard,Guillaume Laconde,Vanessa Delfosse,Tiphaine Huet,Margaux Ayeul,Emilie Rigal,Quentin Donati,Sabine Gerbal-Chaloin,Martine Daujat-Chavanieu,Luc Brunel,Baptiste Legrand,Alain Chavanieu,Anthony R Martin,Julie Pannequin,William Bourguet,Muriel Amblard,Jean Marc Pascussi

Infection and drug resistance 14:1573-1584 PubMed33911883

2021

Overexpression of microRNA-340-5p Ameliorates Inflammatory Response and Intracellular Survival of in Alveolar Type II Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Bailing Zhang,Honglang Li,Jieling Zhang,Yaping Hang,Yi Xu
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
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