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AB272567

Anti-TMEM141 antibody

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Rabbit Polyclonal TMEM141 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM141 aa 50 to C-terminus.

View Alternative Names

Transmembrane protein 141, TMEM141

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-TMEM141 antibody (AB272567)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-TMEM141 antibody (AB272567)

PFA fixed, Triton X-100 permeablized human cell line Caco-2 labeling TMEM141 (green) using ab272567 at 2 ug/ml in ICC/IF analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM141 antibody (AB272567)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM141 antibody (AB272567)

Paraffin-embedded formalin-fixed Human prostate tissue stained for TMEM141 using ab272567 1/200 in immunohistochemical analysis.

Western blot - Anti-TMEM141 antibody (AB272567)
  • WB

Unknown

Western blot - Anti-TMEM141 antibody (AB272567)

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Western blot - Anti-TMEM141 antibody (ab272567)

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Western blot - Anti-TMEM141 antibody (ab272567) at 0.4 µg/mL

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Molecular weight ladder

Lane 2:

RT4

Lane 3:

U-251 MG sp

Predicted band size: 12 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human TMEM141 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q96I45

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMEM141 also known as transmembrane protein 141 is a lesser-known protein with an estimated molecular mass of approximately 36 kDa. This protein is integrated into the membrane playing roles in various cellular processes. Researchers observe its expression in multiple tissues though detailed distribution data remains limited. Current studies aim to better understand its mechanical operations within cellular membranes.
Biological function summary

TMEM141 appears to partake in cellular communication and transport activities. Researchers suggest it may involve membrane-spanning complexes facilitating interactions between intracellular components and extracellular environments. While direct evidence of associated molecular complexes is scant its function posits a possible role in signal transduction or intracellular transport mechanisms that would benefit from such organization.

Pathways

TMEM141 seems to interact within cellular signaling and transport pathways. Although comprehensive mapping remains ongoing some reports indicate interactions with proteins involved in endocytosis and exocytosis pathways. It may work alongside proteins like clathrin or Rab family members to influence these critical cellular processes maintaining cellular homeostasis and response to external stimuli.

Emerging studies hint at TMEM141’s potential link to metabolic diseases and certain cancers. Some investigations connect it to altered metabolic pathways perhaps through its interaction with proteins like PPARs (Peroxisome Proliferator-Activated Receptors) in metabolic syndromes. In oncology alterations in its expression or function could influence cancer cell metabolism or growth though more research is necessary to solidify these connections.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information TMEM141
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Product promise

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