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AB243580

Anti-TMEM151A antibody

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(1 Publication)

Rabbit Polyclonal TMEM151A antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM151A aa 1-50.

View Alternative Names

TMEM151, TMEM151A, Transmembrane protein 151A

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM151A antibody (AB243580)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM151A antibody (AB243580)

Paraffin-embedded human hippocampus tissue stained for TMEM151A using ab243580 at 1/50 dilution in immunohistochemical analysis.

Western blot - Anti-TMEM151A antibody (AB243580)
  • WB

Supplier Data

Western blot - Anti-TMEM151A antibody (AB243580)

All lanes:

Western blot - Anti-TMEM151A antibody (ab243580) at 0.4 µg/mL

Lane 1:

Vector transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

Lane 2:

HEK-293T overexpressing TMEM151A with C-terminal myc-DDK tag, cell lysate

Predicted band size: 51 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human TMEM151A aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q8N4L1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMEM151A also known as Transmembrane Protein 151A is a protein encoded by the TMEM151A gene. This protein has a molecular weight of approximately 23 kDa. It is predominantly expressed in neural tissues such as the brain indicating a possible role in central nervous system functions. TMEM151A has not been extensively studied but current data suggest its involvement as a component of cellular signaling related to membranes.
Biological function summary

TMEM151A aligns with processes that involve neurotransmitter regulation. Research implies its role within the neural synaptic environment though it may not form part of a larger complex. TMEM151A appears to influence synaptic activity and neuronal communication. Its presence in the nervous system especially within the synaptic membranes suggests TMEM151A might contribute to signaling mechanisms necessary for brain function.

Pathways

TMEM151A is believed to contribute to neurotransmitter signaling pathways that manage synaptic transmission and plasticity. These pathways are essential for cognitive functions including learning and memory. Another related protein Synaptotagmin possibly interacts with TMEM151A due to its role in vesicle fusion and neurotransmitter release indicating a functional linkage within neural activities. Detailed studies into its pathway activities could further clarify its exact mechanistic contribution.

Research associates TMEM151A with neurological conditions like epilepsy and neurodegenerative processes. Studies have noted potential interactions with proteins such as GABRA1 which impacts inhibitory neurotransmission and is linked to seizure disorders. Understanding TMEM151A's influence could aid in developing therapeutic strategies for related brain disorders potentially targeting its regulatory role in neuronal pathways involved in these conditions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information TMEM151A
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in bioengineering and biotechnology 13:1581019 PubMed40453182

2025

Development of a procedure for isolation, identification and quality assessment of bovine spermatids and evaluation of their fertilizing ability .

Applications

Unspecified application

Species

Unspecified reactive species

Rolando Pasquariello,Francesca Di Filippo,Sai Kamal Nag Bonumallu,Fernanda Fagali Franchi,Ramona Pistucci,Federica Franciosi,Valentina Lodde,Alessandra Iannuzzi,Alberto Maria Luciano,Tiziana A L Brevini,Fulvio Gandolfi
View all publications
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Product promise

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