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AB106702

Anti-TMEM184A antibody

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(1 Publication)

Rabbit Polyclonal TMEM184A antibody. Suitable for WB and reacts with Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human Transmembrane protein 184A.

View Alternative Names

Transmembrane protein 184A, TMEM184A

1 Images
Western blot - Anti-TMEM184A antibody (AB106702)
  • WB

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Western blot - Anti-TMEM184A antibody (AB106702)

Western Blot of rat brain tissue lysate labeling TMEM184A with Anti-TMEM184A antibody (ab106702) at 1μg/ml in (1) the absence and (2) the presence of blocking peptide.

All lanes:

Western blot - Anti-TMEM184A antibody (ab106702)

Predicted band size: 45 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat

Applications

WB

applications

Immunogen

Synthetic Peptide within Human Transmembrane protein 184A. The exact immunogen used to generate this antibody is proprietary information.

Q6ZMB5

Specificity

ab106702 is predicted to not cross-react with other members of the TMEM184 family.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Stable for 12 months at -20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMEM184A also known as Transmembrane Protein 184A is a protein with a molecular mass of approximately 45 kDa. This protein is a transmembrane protein involved in intracellular signaling. Researchers have found it expressed in a range of tissues including the nervous system reproductive organs and various smooth muscles. Its expression pattern suggests a role in cellular communication particularly in environments that require precise signaling.
Biological function summary

TMEM184A interacts with cellular membranes to influence endocytic processes. It plays a role in regulating the trafficking of specific cargo within the cell affecting how cells respond to external signals. While TMEM184A does not operate as part of a larger static complex it is known to dynamically interact with other membrane proteins and lipids adjusting its role depending on the cellular environment and context.

Pathways

This transmembrane protein influences the G protein-coupled receptor (GPCR) signaling pathway. TMEM184A has been observed to modulate receptor activities affecting downstream signaling cascades. It interacts with proteins like beta-arrestins which are critical for terminating the GPCR signals. By influencing GPCR pathways TMEM184A plays an important role in modulating various physiological processes including neural signaling and smooth muscle contraction.

TMEM184A has connections to conditions such as neuropathies and reproductive system disorders. For instance malfunction in its regulation or expression may contribute to peripheral neuropathy possibly through interactions with proteins that regulate nerve fiber maintenance. Additionally deviant TMEM184A activity can relate to reproductive disorders where its interaction with proteins involved in cell adhesion and signaling becomes disrupted impacting fertility and reproductive health.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity).
See full target information Transmembrane protein 184A
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Metabolites 10: PubMed32235559

2020

Enhancing Glycolysis Protects against Ischemia-Reperfusion Injury by Reducing ROS Production.

Applications

Unspecified application

Species

Unspecified reactive species

Claudia Beltran,Rosario Pardo,Diana Bou-Teen,Marisol Ruiz-Meana,Josep A Villena,Ignacio Ferreira-González,Ignasi Barba
View all publications
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