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AB106719

Anti-TMEM184C antibody

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(1 Publication)

Rabbit Polyclonal TMEM184C antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human TMEM184C.

View Alternative Names

TMEM34, PRO1355, TMEM184C, Transmembrane protein 184C, Transmembrane protein 34

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-TMEM184C antibody (AB106719)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-TMEM184C antibody (AB106719)

Immunofluorescence of TMEM184C in mouse heart tissue with ab106719 at 20 ug/mL.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM184C antibody (AB106719)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM184C antibody (AB106719)

ab106719, at 5 μg/ml, staining paraffin embedded Mouse heart tissue by Immunohistochemistry.

Western blot - Anti-TMEM184C antibody (AB106719)
  • WB

Unknown

Western blot - Anti-TMEM184C antibody (AB106719)

All lanes:

Western blot - Anti-TMEM184C antibody (ab106719) at 1 µg/mL

All lanes:

Mouse heart tissue lysate at 15 µg

Predicted band size: 50 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Synthetic Peptide within Human TMEM184C. The exact immunogen used to generate this antibody is proprietary information.

Q9NVA4

Specificity

ab106719 predicted to not crossreact with other members of the TMEM184 protein family.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "20 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
Up to 12 months
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMEM184C also known as Transmembrane Protein 184C is a membrane protein involved in cellular transport mechanisms. It has a molecular mass of approximately 37.5 kDa. Researchers observe its expression across different tissues including brain heart and skeletal muscle indicating its diverse functional roles. The protein's presence in varied tissues suggests its involvement in broad physiological processes.
Biological function summary

TMEM184C modulates key mechanisms involved in cellular transport and signaling pathways. It participates in facilitating communication between cellular compartments. TMEM184C does not generally associate with large protein complexes emphasizing its role as a more independent functional unit. The protein contributes to maintaining cellular homeostasis through modulation of signaling proteins and transporters.

Pathways

TMEM184C plays a role in maintaining cellular signaling integrity and nutrient transport. It demonstrates connections with the MAPK/ERK signaling pathway influencing cellular response to external stimuli. TMEM184C associates with proteins in this pathway such as ERK to regulate processes related to cell survival and proliferation. Its involvement in the PI3K-Akt pathway also suggests a role in regulating cell growth and glucose metabolism.

TMEM184C associates with certain neurological disorders and metabolic syndromes. Dysfunction or altered expression of TMEM184C could influence diseases like Alzheimer's due to its role in neural signaling pathways. Additionally metabolic conditions like type 2 diabetes may be linked to TMEM184C via its participation in the PI3K-Akt pathway and regulation of insulin signaling proteins. These associations highlight the importance of TMEM184C in maintaining normal physiological function and its potential as a therapeutic target.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Possible tumor suppressor which may play a role in cell growth.
See full target information TMEM184C
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

BMC pharmacology & toxicology 23:92 PubMed36476246

2022

Morphine suppresses the immune function of lung cancer by up-regulating MAEL expression.

Applications

Unspecified application

Species

Unspecified reactive species

Qichao Wang,Zhenfu Liu,Shuhong Tang,Zhen Wu
View all publications
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Product promise

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For full details, please see our Terms & Conditions

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